Rapidly fatal acute bacterial myocarditis in a nonneutropenic child with acute lymphoblastic leukemia in remission

Douglas J. Scothorn, Naomi J. Winick, Charles F. Timmons, Naomiand Victor M Aquino

Research output: Contribution to journalArticle

Abstract

The authors report a fatal case of acute bacterial myocarditis in a nonneutropenic child with acute lymphoblastic leukemia. She was admitted to the hospital with a urinary tract infection resulting from Klebsiella pneumoniae and remained persistently febrile despite resolution of the infection. On hospital day 4 signs of acute cardiac failure developed. Despite aggressive resuscitation measures, she died. Pathologic examination revealed the cause of death to be bacterial myocarditis. In addition, she was found to have a generalized decrease in her serum immunoglobulin levels. Acute bacterial myocarditis in patients with malignancy has been rarely reported. The rapid clinical deterioration and death in the patient in this report is particularly interesting.

Original languageEnglish (US)
Pages (from-to)662-665
Number of pages4
JournalJournal of Pediatric Hematology/Oncology
Volume24
Issue number8
DOIs
StatePublished - Nov 2002

Keywords

  • Acute lymphoblastic leukemia
  • Bacterial myocarditis
  • Klebsiella pneumoniae

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

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