Rare Pediatric Malignancies of the Head and Neck

Ted A. James, Larry L. Myers, Nestor Rigual, Janet S. Winston, Thom R. Loree, Wesley L. Hicks

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Malignant head and neck neoplasms are rare occurrences in the pediatric population, and account for approximately 10% of all pediatric tumors. Less commonly encountered pediatric head and neck tumors include extraosseous Ewing's sarcoma (EOE), ameloblastoma odontogenic tumors, sinonasal undifferentiated carcinoma (SNUC), and esthesioneuroblastoma. Knowledge of the current management of these rare head and neck malignancies is essential in delivering optimal care and achieving favorable outcomes. Treatment strategies are similar to those applied to adults with the same neoplastic process, and include a multidisciplinary combination of surgery, radiation, and chemotherapy. However, it is important to be aware of the specific pathophysiology and tumor biology seen in pediatric malignancies. Close posttreatment surveillance is necessary as adverse effects may arise several years following cancer treatment. The following review will outline the biology and treatment of select rare pediatric head and neck malignancies.

Original languageEnglish (US)
Title of host publicationTextbook of Uncommon Cancer, Third Edition
PublisherJohn Wiley & Sons, Ltd
Pages721-731
Number of pages11
ISBN (Print)0470012021, 9780470012024
DOIs
Publication statusPublished - Jul 11 2006

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Keywords

  • Head and neck
  • Malignancy
  • Pediatric
  • Tumors

ASJC Scopus subject areas

  • Medicine(all)

Cite this

James, T. A., Myers, L. L., Rigual, N., Winston, J. S., Loree, T. R., & Hicks, W. L. (2006). Rare Pediatric Malignancies of the Head and Neck. In Textbook of Uncommon Cancer, Third Edition (pp. 721-731). John Wiley & Sons, Ltd. https://doi.org/10.1002/0470030542.ch66