Reactivity of γ-chloro-gem-trichloroalkanes with chromous chloride

Steve Tisserand, Romain Bejot, Célia Billaud, De Run Li, J. R. Falck, Charles Mioskowski

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

CrCl2-mediated condensation of γ-chloro-gem-trichloroalkanes with aldehyde generates homoallylic alcohols through a hydride rearrangement followed by a Nozaki-Hiyama allylation.

Original languageEnglish (US)
Pages (from-to)5177-5180
Number of pages4
JournalTetrahedron Letters
Volume47
Issue number29
DOIs
StatePublished - Jul 17 2006

Keywords

  • Carbene
  • Chromium
  • Nozaki-Hiyama allylation
  • Trichloroalkane

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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  • Cite this

    Tisserand, S., Bejot, R., Billaud, C., Li, D. R., Falck, J. R., & Mioskowski, C. (2006). Reactivity of γ-chloro-gem-trichloroalkanes with chromous chloride. Tetrahedron Letters, 47(29), 5177-5180. https://doi.org/10.1016/j.tetlet.2006.05.045