Ready for Prime Time? Biomarkers in Sepsis

Brit Long, Alex Koyfman

Research output: Contribution to journalReview articlepeer-review

17 Scopus citations

Abstract

Sepsis is a common condition managed in the emergency department. Current diagnosis relies on physiologic criteria and suspicion of a source of infection using history, physical examination, laboratory studies, and imaging studies. The infection triggers a host response with the aim to destroy the pathogen, and this response can be measured. A reliable biomarker for sepsis should assist with earlier diagnosis, improve risk stratification, or improve clinical decision making. Current biomarkers for sepsis include lactate, troponin, and procalcitonin. This article discusses the use of lactate, procalcitonin, troponin, and novel biomarkers for use in sepsis.

Original languageEnglish (US)
Pages (from-to)109-122
Number of pages14
JournalEmergency Medicine Clinics of North America
Volume35
Issue number1
DOIs
StatePublished - Feb 1 2017

Keywords

  • Biomarkers
  • Lactate
  • Proadrenomedullin
  • Procalcitonin
  • Sepsis
  • Troponin

ASJC Scopus subject areas

  • Emergency Medicine

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