Real-time 3D Fourier-domain optical coherence tomography guided microvascular anastomosis

Yong Huang, Zuhaib Ibrahim, W. P.Andree Lee, Gerald Brandacher, Jin U. Kang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

Vascular and microvascular anastomosis is considered to be the foundation of plastic and reconstructive surgery, hand surgery, transplant surgery, vascular surgery and cardiac surgery. In the last two decades innovative techniques, such as vascular coupling devices, thermo-reversible poloxamers and suture-less cuff have been introduced. Intra-operative surgical guidance using a surgical imaging modality that provides in-depth view and 3D imaging can improve outcome following both conventional and innovative anastomosis techniques. Optical coherence tomography (OCT) is a non-invasive high-resolution (micron level), high-speed, 3D imaging modality that has been adopted widely in biomedical and clinical applications. In this work we performed a proof-of-concept evaluation study of OCT as an assisted intraoperative and post-operative imaging modality for microvascular anastomosis of rodent femoral vessels. The OCT imaging modality provided lateral resolution of 12 μm and 3.0 μm axial resolution in air and 0.27 volume/s imaging speed, which could provide the surgeon with clearly visualized vessel lumen wall and suture needle position relative to the vessel during intraoperative imaging. Graphics processing unit (GPU) accelerated phase-resolved Doppler OCT (PRDOCT) imaging of the surgical site was performed as a post-operative evaluation of the anastomosed vessels and to visualize the blood flow and thrombus formation. This information could help surgeons improve surgical precision in this highly challenging anastomosis of rodent vessels with diameter less than 0.5 mm. Our imaging modality could not only detect accidental suture through the back wall of lumen but also promptly diagnose and predict thrombosis immediately after reperfusion. Hence, real-time OCT can assist in decision-making process intra-operatively and avoid post-operative complications.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2013
Subtitle of host publicationImage-Guided Procedures, Robotic Interventions, and Modeling
DOIs
StatePublished - Jun 10 2013
Externally publishedYes
EventMedical Imaging 2013: Image-Guided Procedures, Robotic Interventions, and Modeling - Lake Buena Vista, FL, United States
Duration: Feb 12 2013Feb 14 2013

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume8671
ISSN (Print)0277-786X

Conference

ConferenceMedical Imaging 2013: Image-Guided Procedures, Robotic Interventions, and Modeling
CountryUnited States
CityLake Buena Vista, FL
Period2/12/132/14/13

Keywords

  • Graphics processing unit
  • Microvascular anastomosis
  • Optical coherence tomography
  • Phase-resolved Doppler

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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  • Cite this

    Huang, Y., Ibrahim, Z., Lee, W. P. A., Brandacher, G., & Kang, J. U. (2013). Real-time 3D Fourier-domain optical coherence tomography guided microvascular anastomosis. In Medical Imaging 2013: Image-Guided Procedures, Robotic Interventions, and Modeling [86711H] (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 8671). https://doi.org/10.1117/12.2008020