Abstract
Head motion artifacts are a major problem in functional MRI that limit its use in neuroscience research and clinical settings. Real-time scan-plane correction by optical tracking has been shown to correct slice misalignment and nonlinear spin-history artifacts; however, residual artifacts due to dynamic magnetic field nonuniformity may remain in the data. A recently developed correction technique, Phase Labeling for Additional Coordinate Encoding, can correct for absolute geometric distortion using only the complex image data from two echo planar images with slightly shifted k-space trajectories. An approach is presented that integrates Phase Labeling for Additional Coordinate Encoding into a real-time scan-plane update system by optical tracking, applied to a tissue-equivalent phantom undergoing complex motion and an functional MRI finger tapping experiment with overt head motion to induce dynamic field nonuniformity. Experiments suggest that such integrated volume-by-volume corrections are very effective at artifact suppression, with potential to expand functional MRI applications.
Original language | English (US) |
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Pages (from-to) | 734-748 |
Number of pages | 15 |
Journal | Magnetic resonance in medicine |
Volume | 69 |
Issue number | 3 |
DOIs | |
State | Published - Mar 1 2013 |
Keywords
- PLACE
- echo planar imaging
- functional magnetic resonance imaging
- geometric distortion correction
- optical tracking
- real-time motion correction
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging