Real-time H-scan ultrasound imaging using a Verasonics research scanner

Mawia Khairalseed, Katherine Brown, Kevin J. Parker, Kenneth Hoyt

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

H-scan ultrasound (US) is a new imaging technique that relies on matching a model that describes US image formation to the mathematics of a class of Gaussian-weighted Hermite polynomials (GH). In short, H-scan US (where the ‘H’ denotes Hermite or hue) is a tissue classification technique that images the relative size of acoustic scatterers. Herein, we detail development of a real-time H-scan US imaging technology that was implemented on a programmable US research scanner (Vantage 256, Verasonics Inc, Kirkland, WA). This custom US imaging system has a dual display for real-time visualization of both the H-scan and B-scan US images. This MATLAB-based (Mathworks Inc, Natick, MA) system includes a graphical user interface (GUI) for controlling the entire US scan sequence including the raw radio frequency (RF) data acquisition parameters, image processing, variable control of a parallel set of convolution filters used to derive the H-scan US signal, and data (cine loop) save. The system-level structure used for software-based image reconstruction and display is detailed. Imaging studies were conducted using a series of homogeneous and heterogeneous tissue-mimicking phantom materials embedded with monodisperse spherical US scatterers of size 15–40 µm in diameter. Relative to H-scan US image measurements from a phantom with 15 µm-sized scatterers, data from phantoms with the 30 and 40 µm-sized scatterers exhibited mean intensity increases of 5.2% and 11.6%, respectively. Overall, real-time H-scan US imaging is a promising approach for visualizing the relative size and distribution of acoustic scattering objects.

Original languageEnglish (US)
JournalUltrasonics
DOIs
StateAccepted/In press - Jan 1 2019

Fingerprint

scanners
scattering
acoustic scattering
graphical user interface
mathematics
image reconstruction
convolution integrals
imaging techniques
data acquisition
image processing
radio frequencies
polynomials
computer programs
filters
acoustics

Keywords

  • Acoustic scatterers
  • H-scan
  • Plane waves
  • Spatial angular compounding
  • Tissue characterization
  • Ultrasound

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

Cite this

Real-time H-scan ultrasound imaging using a Verasonics research scanner. / Khairalseed, Mawia; Brown, Katherine; Parker, Kevin J.; Hoyt, Kenneth.

In: Ultrasonics, 01.01.2019.

Research output: Contribution to journalArticle

Khairalseed, Mawia ; Brown, Katherine ; Parker, Kevin J. ; Hoyt, Kenneth. / Real-time H-scan ultrasound imaging using a Verasonics research scanner. In: Ultrasonics. 2019.
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