Recent developments for the efficient crystallographic refinement of macromolecular structures

Axel T. Brünger, Paul D. Adams, Luke M. Rice

Research output: Contribution to journalArticle

81 Citations (Scopus)

Abstract

Macromolecular crystallographic refinement has recently been made more efficient by the use of cross-validated maximum likelihood targets and torsion-angle molecular dynamics simulated annealing. In combination with automated model building methods, the amount of manual intervention required to complete and refine a structure is greatly reduced.

Original languageEnglish (US)
Pages (from-to)606-611
Number of pages6
JournalCurrent Opinion in Structural Biology
Volume8
Issue number5
DOIs
StatePublished - Oct 1998

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Molecular Dynamics Simulation

ASJC Scopus subject areas

  • Molecular Biology
  • Structural Biology

Cite this

Recent developments for the efficient crystallographic refinement of macromolecular structures. / Brünger, Axel T.; Adams, Paul D.; Rice, Luke M.

In: Current Opinion in Structural Biology, Vol. 8, No. 5, 10.1998, p. 606-611.

Research output: Contribution to journalArticle

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