Abstract
Here we present direct evidence for the vital role of RecO in Deinococcus radioduran's radioresistance. A recO null mutant was constructed using a deletion replacement method. The mutant exhibited a growth defect and extreme sensitivity to irradiation with gamma rays and UV light. These results suggest that DNA repair in this organism occurs mainly via the RecF pathway.
Original language | English (US) |
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Pages (from-to) | 2624-2628 |
Number of pages | 5 |
Journal | Journal of bacteriology |
Volume | 190 |
Issue number | 7 |
DOIs | |
State | Published - Apr 2008 |
ASJC Scopus subject areas
- Microbiology
- Molecular Biology