Recognition of non-self-polysaccharides by C-type lectin receptors dectin-1 and dectin-2

S. Tyler Hollmig; Kiyoshi Ariizumi; Ponciano D Cruz

doi:10.1093/glycob/cwp032

Recognition of non-self-polysaccharides by C-type lectin receptors dectin-1 and dectin-2

S. Tyler Hollmig, Kiyoshi Ariizumi, Ponciano D Cruz

Research output: Contribution to journal › Review article › peer-review

47 Scopus citations

Abstract

The discovery of several transmembrane receptors expressed by antigen presenting cells, including those that detect and interact with specific sugar moieties on the surface of microbes, has improved our understanding of how immunity against infection is generated. This knowledge, in turn, prompted us to review such interactions with emphasis on C-type lectin receptors and a focus on the roles of dectin-1 and dectin-2 in anti-fungal immunity.

Original language	English (US)
Pages (from-to)	568-575
Number of pages	8
Journal	Glycobiology
Volume	19
Issue number	6
DOIs	https://doi.org/10.1093/glycob/cwp032
State	Published - 2009

ASJC Scopus subject areas

Biochemistry

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abstract = "The discovery of several transmembrane receptors expressed by antigen presenting cells, including those that detect and interact with specific sugar moieties on the surface of microbes, has improved our understanding of how immunity against infection is generated. This knowledge, in turn, prompted us to review such interactions with emphasis on C-type lectin receptors and a focus on the roles of dectin-1 and dectin-2 in anti-fungal immunity.",

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N1 - Funding Information: Funding from the National Institutes of Health, USA.

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N2 - The discovery of several transmembrane receptors expressed by antigen presenting cells, including those that detect and interact with specific sugar moieties on the surface of microbes, has improved our understanding of how immunity against infection is generated. This knowledge, in turn, prompted us to review such interactions with emphasis on C-type lectin receptors and a focus on the roles of dectin-1 and dectin-2 in anti-fungal immunity.

AB - The discovery of several transmembrane receptors expressed by antigen presenting cells, including those that detect and interact with specific sugar moieties on the surface of microbes, has improved our understanding of how immunity against infection is generated. This knowledge, in turn, prompted us to review such interactions with emphasis on C-type lectin receptors and a focus on the roles of dectin-1 and dectin-2 in anti-fungal immunity.

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Recognition of non-self-polysaccharides by C-type lectin receptors dectin-1 and dectin-2

Abstract

ASJC Scopus subject areas

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