Recurrent Burkholderia infection in patients with chronic granulomatous disease: 11-Year experience at a large referral center

David E. Greenberg, Joanna B. Goldberg, Frida Stock, Patrick R. Murray, Steven M. Holland, John J. Lipuma

Research output: Contribution to journalArticlepeer-review

31 Scopus citations

Abstract

The epidemiology of Burkholderia infection in persons with chronic granulomatous disease is poorly understood. We used species-specific polymerase chain reaction-based assays and genotyping analyses to identify 32 strains representing 9 Burkholderia species among 50 isolates recovered from 18 patients with chronic granulomatous disease. We found that recurrent pulmonary infection with distinct Burkholderia strains is common in chronic granulomatous disease.

Original languageEnglish (US)
Pages (from-to)1577-1579
Number of pages3
JournalClinical Infectious Diseases
Volume48
Issue number11
DOIs
StatePublished - Jun 1 2009

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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