Recurrent Burkholderia infection in patients with chronic granulomatous disease

11-Year experience at a large referral center

David E. Greenberg, Joanna B. Goldberg, Frida Stock, Patrick R. Murray, Steven M. Holland, John J. Lipuma

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

The epidemiology of Burkholderia infection in persons with chronic granulomatous disease is poorly understood. We used species-specific polymerase chain reaction-based assays and genotyping analyses to identify 32 strains representing 9 Burkholderia species among 50 isolates recovered from 18 patients with chronic granulomatous disease. We found that recurrent pulmonary infection with distinct Burkholderia strains is common in chronic granulomatous disease.

Original languageEnglish (US)
Pages (from-to)1577-1579
Number of pages3
JournalClinical Infectious Diseases
Volume48
Issue number11
DOIs
StatePublished - Jun 1 2009

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Burkholderia Infections
Chronic Granulomatous Disease
Burkholderia
Referral and Consultation
Epidemiology
Polymerase Chain Reaction
Lung
Infection

ASJC Scopus subject areas

  • Infectious Diseases
  • Microbiology (medical)
  • Medicine(all)

Cite this

Recurrent Burkholderia infection in patients with chronic granulomatous disease : 11-Year experience at a large referral center. / Greenberg, David E.; Goldberg, Joanna B.; Stock, Frida; Murray, Patrick R.; Holland, Steven M.; Lipuma, John J.

In: Clinical Infectious Diseases, Vol. 48, No. 11, 01.06.2009, p. 1577-1579.

Research output: Contribution to journalArticle

Greenberg, David E. ; Goldberg, Joanna B. ; Stock, Frida ; Murray, Patrick R. ; Holland, Steven M. ; Lipuma, John J. / Recurrent Burkholderia infection in patients with chronic granulomatous disease : 11-Year experience at a large referral center. In: Clinical Infectious Diseases. 2009 ; Vol. 48, No. 11. pp. 1577-1579.
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