Abstract
Background: The aim of this study was to examine clinical factors associated with the recurrence of community-onset skin and soft tissue infections caused by methicillin-resistant Staphylococcus aureus. Methods: An observational case-comparison study based on a retrospective review of medical records was conducted in a public health system. All patients with community-onset skin and soft tissue infections caused by methicillin-resistant S aureus who underwent operative debridement from January 1999 to December 2003 were included. The outcome of interest was recurrence within 1 year. Results: Two hundred fifty-three patients met the criteria for inclusion. Fifty-three (21%) patients returned with recurrent episodes. These patients were compared with 200 patients (79%) who did not develop recurrence. On multivariate analysis, factors independently predictive of recurrence were medical history of abscess requiring surgical debridement within the previous year (adjusted odds ratio, 2.6; 95% confidence interval, 1.45.0; P = .002) and obesity (adjusted odds ratio, 3.4; 95% confidence interval, 1.48.8; P = .008). Conclusions: Patients with obesity or histories of methicillin-resistant S aureus infection are at significantly increased risk for recurrent soft tissue infection.
Original language | English (US) |
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Pages (from-to) | 216-220 |
Number of pages | 5 |
Journal | American journal of surgery |
Volume | 201 |
Issue number | 2 |
DOIs | |
State | Published - Feb 2011 |
Keywords
- Abscess
- Epidemiology
- Methicillin-resistant Staphylococcus aureus
- Recurrence
- Risk factors
- Staphylococcal infections
- Staphylococcal skin infections
- Staphylococcus aureus
ASJC Scopus subject areas
- Surgery