Reduction of Carbonyl Function to a Methyl Group

Gan B. Bajracharya, Tsutomu Nogami, Tienan Jin, Kumiko Matsuda, Vladimir Gevorgyan, Yoshinori Yamamoto

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

A direct exhaustive reduction of aliphatic carbonyl functions (aldehydes, acyl chlorides, esters and carboxylic acids) to a methyl group by triethylsilane (Et3SiH) in the presence of catalytic amount of tris(pentafluorophenyl)borane [B(C6F5)3] is described. Aromatic carbonyl functions could undergo partial reduction to the corresponding TES-protected benzylic alcohols.

Original languageEnglish (US)
Pages (from-to)308-311
Number of pages4
JournalSynthesis
Issue number2
DOIs
StatePublished - Feb 2 2004
Externally publishedYes

Fingerprint

Carboxylic Acids
Aldehydes
Carboxylic acids
Chlorides
Esters
Alcohols
triethylsilane
tris(pentafluorophenyl)borane
TES

Keywords

  • Acyl chlorides
  • Aldehydes
  • Carboxylic acids
  • Esters
  • Reductions

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

Cite this

Bajracharya, G. B., Nogami, T., Jin, T., Matsuda, K., Gevorgyan, V., & Yamamoto, Y. (2004). Reduction of Carbonyl Function to a Methyl Group. Synthesis, (2), 308-311. https://doi.org/10.1055/s-2003-44356

Reduction of Carbonyl Function to a Methyl Group. / Bajracharya, Gan B.; Nogami, Tsutomu; Jin, Tienan; Matsuda, Kumiko; Gevorgyan, Vladimir; Yamamoto, Yoshinori.

In: Synthesis, No. 2, 02.02.2004, p. 308-311.

Research output: Contribution to journalArticle

Bajracharya, GB, Nogami, T, Jin, T, Matsuda, K, Gevorgyan, V & Yamamoto, Y 2004, 'Reduction of Carbonyl Function to a Methyl Group', Synthesis, no. 2, pp. 308-311. https://doi.org/10.1055/s-2003-44356
Bajracharya GB, Nogami T, Jin T, Matsuda K, Gevorgyan V, Yamamoto Y. Reduction of Carbonyl Function to a Methyl Group. Synthesis. 2004 Feb 2;(2):308-311. https://doi.org/10.1055/s-2003-44356
Bajracharya, Gan B. ; Nogami, Tsutomu ; Jin, Tienan ; Matsuda, Kumiko ; Gevorgyan, Vladimir ; Yamamoto, Yoshinori. / Reduction of Carbonyl Function to a Methyl Group. In: Synthesis. 2004 ; No. 2. pp. 308-311.
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