TY - JOUR
T1 - Reduction of cerebellar volume in major depression
T2 - A controlled MRI study
AU - Escalona, P. Rodrigo
AU - Early, Bridget
AU - McDonald, William M.
AU - Doraiswamy, P. Murali
AU - Shah, Sunjay A.
AU - Husain, Mustafa M.
AU - Boyko, Orest B.
AU - Figiel, Gary S.
AU - Ellinwood, Everett H.
AU - Nemeroff, Charles B.
AU - Krishnan, K. Ranga R
PY - 1993
Y1 - 1993
N2 - A systematic sampling stereological method of serially acquired axial intermediate T2‐weighted Spin echo magnetic resonance imaging (MRI) of the brain was used to measure cerebellar volume in 30 patients who fulfilled DSM III criteria for major depression and compared with 35 normal controls. The mean cerebellar volume of depressed patients was significantly smaller than the controls. This preliminary study adds new evidence for the possible participation of the cerebellum in the pathophysiology of major depression and warrants further investigation in this area. Depression 1:156–158 (1993). © 1993 Wiley‐Liss, Inc.
AB - A systematic sampling stereological method of serially acquired axial intermediate T2‐weighted Spin echo magnetic resonance imaging (MRI) of the brain was used to measure cerebellar volume in 30 patients who fulfilled DSM III criteria for major depression and compared with 35 normal controls. The mean cerebellar volume of depressed patients was significantly smaller than the controls. This preliminary study adds new evidence for the possible participation of the cerebellum in the pathophysiology of major depression and warrants further investigation in this area. Depression 1:156–158 (1993). © 1993 Wiley‐Liss, Inc.
KW - cerebellum
KW - magnetic resonance imaging
KW - major depression
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U2 - 10.1002/depr.3050010307
DO - 10.1002/depr.3050010307
M3 - Article
AN - SCOPUS:85005299883
SN - 1062-6417
VL - 1
SP - 156
EP - 158
JO - Depression
JF - Depression
IS - 3
ER -