Reductive lithiation of bis-phenylsulfones

Jurong Yu, Hyun Sung Cho, S. Chandrasekhar, J R Falck, Charles Mioskowski

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


Reductive cleavage of geminal bis-phenylsulfones using lithium naphthalenide in THF at -78°C selectively affords α-sulfonyl carbanions which participate in typical reaction with electrophiles.

Original languageEnglish (US)
Pages (from-to)5437-5440
Number of pages4
JournalTetrahedron Letters
Issue number30
StatePublished - Jul 25 1994


  • alkylation
  • desulfonylation
  • lithium naphthalenide
  • α-sulfonyl carbanion

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Reductive lithiation of bis-phenylsulfones'. Together they form a unique fingerprint.

Cite this