Reductive lithiation of bis-phenylsulfones

Jurong Yu, Hyun Sung Cho, S. Chandrasekhar, J R Falck, Charles Mioskowski

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Reductive cleavage of geminal bis-phenylsulfones using lithium naphthalenide in THF at -78°C selectively affords α-sulfonyl carbanions which participate in typical reaction with electrophiles.

Original languageEnglish (US)
Pages (from-to)5437-5440
Number of pages4
JournalTetrahedron Letters
Volume35
Issue number30
DOIs
StatePublished - Jul 25 1994

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Lithium

Keywords

  • alkylation
  • desulfonylation
  • lithium naphthalenide
  • α-sulfonyl carbanion

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Yu, J., Cho, H. S., Chandrasekhar, S., Falck, J. R., & Mioskowski, C. (1994). Reductive lithiation of bis-phenylsulfones. Tetrahedron Letters, 35(30), 5437-5440. https://doi.org/10.1016/S0040-4039(00)73519-2

Reductive lithiation of bis-phenylsulfones. / Yu, Jurong; Cho, Hyun Sung; Chandrasekhar, S.; Falck, J R; Mioskowski, Charles.

In: Tetrahedron Letters, Vol. 35, No. 30, 25.07.1994, p. 5437-5440.

Research output: Contribution to journalArticle

Yu, J, Cho, HS, Chandrasekhar, S, Falck, JR & Mioskowski, C 1994, 'Reductive lithiation of bis-phenylsulfones', Tetrahedron Letters, vol. 35, no. 30, pp. 5437-5440. https://doi.org/10.1016/S0040-4039(00)73519-2
Yu J, Cho HS, Chandrasekhar S, Falck JR, Mioskowski C. Reductive lithiation of bis-phenylsulfones. Tetrahedron Letters. 1994 Jul 25;35(30):5437-5440. https://doi.org/10.1016/S0040-4039(00)73519-2
Yu, Jurong ; Cho, Hyun Sung ; Chandrasekhar, S. ; Falck, J R ; Mioskowski, Charles. / Reductive lithiation of bis-phenylsulfones. In: Tetrahedron Letters. 1994 ; Vol. 35, No. 30. pp. 5437-5440.
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