Refractory Gastroesophageal Reflux Disease and Functional Heartburn

Stuart Jon Spechler

doi:10.1016/j.giec.2019.12.003

Refractory Gastroesophageal Reflux Disease and Functional Heartburn

Stuart Jon Spechler

Research output: Contribution to journal › Review article › peer-review

11 Scopus citations

Abstract

This report discusses the potential mechanisms that might underlie refractory GERD and functional heartburn, and how to distinguish among those mechanisms using a systematic evaluation that includes careful medical history, endoscopy with esophageal biopsy, esophageal manometry, and esophageal multichannel intraluminal impedance-pH monitoring. The report provides an approach to patient management that depends on the underlying mechanism identified by this systematic evaluation.

Original language	English (US)
Pages (from-to)	343-359
Number of pages	17
Journal	Gastrointestinal Endoscopy Clinics of North America
Volume	30
Issue number	2
DOIs	https://doi.org/10.1016/j.giec.2019.12.003
State	Published - Apr 2020
Externally published	Yes

Keywords

Functional heartburn
Fundoplication
Gastroesophageal reflux disease
Magnetic sphincter augmentation
Proton pump inhibitor
Reflux hypersensitivity

ASJC Scopus subject areas

Gastroenterology

Access to Document

10.1016/j.giec.2019.12.003

Cite this

@article{6b95260752ac4bc0934d95d65ec7556c,

title = "Refractory Gastroesophageal Reflux Disease and Functional Heartburn",

abstract = "This report discusses the potential mechanisms that might underlie refractory GERD and functional heartburn, and how to distinguish among those mechanisms using a systematic evaluation that includes careful medical history, endoscopy with esophageal biopsy, esophageal manometry, and esophageal multichannel intraluminal impedance-pH monitoring. The report provides an approach to patient management that depends on the underlying mechanism identified by this systematic evaluation.",

keywords = "Functional heartburn, Fundoplication, Gastroesophageal reflux disease, Magnetic sphincter augmentation, Proton pump inhibitor, Reflux hypersensitivity",

author = "Spechler, {Stuart Jon}",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Inc.",

year = "2020",

month = apr,

doi = "10.1016/j.giec.2019.12.003",

language = "English (US)",

volume = "30",

pages = "343--359",

journal = "Gastrointestinal Endoscopy Clinics of North America",

issn = "1052-5157",

publisher = "W.B. Saunders Ltd",

number = "2",

}

TY - JOUR

T1 - Refractory Gastroesophageal Reflux Disease and Functional Heartburn

AU - Spechler, Stuart Jon

PY - 2020/4

Y1 - 2020/4

N2 - This report discusses the potential mechanisms that might underlie refractory GERD and functional heartburn, and how to distinguish among those mechanisms using a systematic evaluation that includes careful medical history, endoscopy with esophageal biopsy, esophageal manometry, and esophageal multichannel intraluminal impedance-pH monitoring. The report provides an approach to patient management that depends on the underlying mechanism identified by this systematic evaluation.

AB - This report discusses the potential mechanisms that might underlie refractory GERD and functional heartburn, and how to distinguish among those mechanisms using a systematic evaluation that includes careful medical history, endoscopy with esophageal biopsy, esophageal manometry, and esophageal multichannel intraluminal impedance-pH monitoring. The report provides an approach to patient management that depends on the underlying mechanism identified by this systematic evaluation.

KW - Functional heartburn

KW - Fundoplication

KW - Gastroesophageal reflux disease

KW - Magnetic sphincter augmentation

KW - Proton pump inhibitor

KW - Reflux hypersensitivity

UR - http://www.scopus.com/inward/record.url?scp=85078140113&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85078140113&partnerID=8YFLogxK

U2 - 10.1016/j.giec.2019.12.003

DO - 10.1016/j.giec.2019.12.003

M3 - Review article

C2 - 32146950

AN - SCOPUS:85078140113

SN - 1052-5157

VL - 30

SP - 343

EP - 359

JO - Gastrointestinal Endoscopy Clinics of North America

JF - Gastrointestinal Endoscopy Clinics of North America

IS - 2

ER -

Refractory Gastroesophageal Reflux Disease and Functional Heartburn

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this