Regional variation in hip fracture incidence among Japanese hemodialysis patients

Minako Wakasugi, Junichiro James Kazama, Atsushi Wada, Masatomo Taniguchi, Yoshiharu Tsubakihara, Kunitoshi Iseki, Ichiei Narita

Research output: Contribution to journalArticle

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Abstract

Hip fracture incidence in Japanese hemodialysis patients is five-fold higher than in the general population, although the mechanisms underlying this difference are not fully understood. Substantial regional variation exists in hip fracture incidence in the general Japanese population, despite a uniform health care and insurance system and lack of ethnic and racial variation. In this study, we determined whether the regional variation seen in the general population also applies to hemodialysis patients in Japan. Standardized incidence ratios were calculated for each regional district, and regional variations of hip fracture incidence among hemodialysis patients were evaluated using data obtained from the Japanese Society for Dialysis Therapy registry (data collected from December 2007 to December 2008). Standardized hip fracture incidence ratios across the districts ranged from 0.71 to 1.29 for male and 0.49 to 1.36 for female hemodialysis patients. Incidence ratios tended to be higher in western Japan and lower in eastern Japan, suggesting that regional variation also exists among hemodialysis patients. Our findings suggest that common risk factors for hip fracture may be shared among the general population and hemodialysis patients. Further research aimed at identifying factors, including those associated with regional variation, may help decrease hip fracture incidence in both the general population and hemodialysis patients in Japan.

Original languageEnglish (US)
Pages (from-to)162-166
Number of pages5
JournalTherapeutic Apheresis and Dialysis
Volume18
Issue number2
DOIs
StatePublished - 2014

Fingerprint

Hip Fractures
Renal Dialysis
Incidence
Japan
Population
Health Insurance
Registries
Dialysis
Delivery of Health Care
Research

Keywords

  • General population
  • Hemodialysis patients
  • Hip fracture
  • Incidence
  • Regional variation

ASJC Scopus subject areas

  • Hematology
  • Nephrology
  • Medicine(all)

Cite this

Wakasugi, M., Kazama, J. J., Wada, A., Taniguchi, M., Tsubakihara, Y., Iseki, K., & Narita, I. (2014). Regional variation in hip fracture incidence among Japanese hemodialysis patients. Therapeutic Apheresis and Dialysis, 18(2), 162-166. https://doi.org/10.1111/1744-9987.12074

Regional variation in hip fracture incidence among Japanese hemodialysis patients. / Wakasugi, Minako; Kazama, Junichiro James; Wada, Atsushi; Taniguchi, Masatomo; Tsubakihara, Yoshiharu; Iseki, Kunitoshi; Narita, Ichiei.

In: Therapeutic Apheresis and Dialysis, Vol. 18, No. 2, 2014, p. 162-166.

Research output: Contribution to journalArticle

Wakasugi, M, Kazama, JJ, Wada, A, Taniguchi, M, Tsubakihara, Y, Iseki, K & Narita, I 2014, 'Regional variation in hip fracture incidence among Japanese hemodialysis patients', Therapeutic Apheresis and Dialysis, vol. 18, no. 2, pp. 162-166. https://doi.org/10.1111/1744-9987.12074
Wakasugi, Minako ; Kazama, Junichiro James ; Wada, Atsushi ; Taniguchi, Masatomo ; Tsubakihara, Yoshiharu ; Iseki, Kunitoshi ; Narita, Ichiei. / Regional variation in hip fracture incidence among Japanese hemodialysis patients. In: Therapeutic Apheresis and Dialysis. 2014 ; Vol. 18, No. 2. pp. 162-166.
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