Regional variation in the incidence of diabetes-related amputations in the Netherlands

W. H. Van Houtum, L. A. Lavery

Research output: Contribution to journalArticle

43 Scopus citations


The purpose of this study is to identify the incidence of diabetes-related lower extremity amputations in 27 health regions in the Netherlands. A secondary database was used that contains all hospitalizations for a lower extremity amputation; in the Netherlands in 1991 and 1992, recorded seperately for 27 health regions. The age-adjusted incidence lower extremity amputations per 10 000 diabetic patients in the Netherlands was 25.05, and among the regions it ranged from 10.15 to 44.64. In the non-diabetic population, the age-adjusted incidence in the Netherlands was 1.24 and ranged by region from 0.77 to 1.77. Overall, diabetic males bad higher age-adjusted incidence rates than diabetic females, although in four health regions the situation was reversed. In the Netherlands, there was an increasing incidence of diabetes-related lower extremity amputation as age increased: <45 years, 11.15; 45-64 years, 33.84; 65-74 years, 61.22; and 75 + years, 107.92 (P < 0.001). This continued to be a significant phenomenon for every health region(P < 0.001). This study found a wide range in the incidence of diabetes related lower extremity amputations in the 27 health regions in the Netherlands. A possible explanation could be differences in the severity of diabetes, in local treatment philosophies or the availability of subspecialties.

Original languageEnglish (US)
Pages (from-to)125-132
Number of pages8
JournalDiabetes Research and Clinical Practice
Issue number1-3
Publication statusPublished - Mar 1996



  • Amputation
  • Diabetes mellitus
  • Epidemiology
  • Foot
  • The Netherlands

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Cite this