Regioselective, Photocatalytic α-Functionalization of Amines

Lingying Leng; Yue Fu; Peng Liu; Joseph M. Ready

doi:10.1021/jacs.0c03758

Regioselective, Photocatalytic α-Functionalization of Amines

Lingying Leng, Yue Fu, Peng Liu, Joseph M. Ready

Research output: Contribution to journal › Article › peer-review

49 Scopus citations

Abstract

Photocatalytic α-functionalization of amines provides a mild and atom-economical means to synthesize α-branched amines. Prior examples featured symmetrical or electronically biased substrates. Here we report a controllable α-functionalization of amines in which regioselectivity can be tuned with minor changes to the reaction conditions.

Original language	English (US)
Pages (from-to)	11972-11977
Number of pages	6
Journal	Journal of the American Chemical Society
Volume	142
Issue number	28
DOIs	https://doi.org/10.1021/jacs.0c03758
State	Published - Jul 15 2020

ASJC Scopus subject areas

Catalysis
General Chemistry
Biochemistry
Colloid and Surface Chemistry

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10.1021/jacs.0c03758

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abstract = "Photocatalytic α-functionalization of amines provides a mild and atom-economical means to synthesize α-branched amines. Prior examples featured symmetrical or electronically biased substrates. Here we report a controllable α-functionalization of amines in which regioselectivity can be tuned with minor changes to the reaction conditions.",

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AU - Liu, Peng

AU - Ready, Joseph M.

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AB - Photocatalytic α-functionalization of amines provides a mild and atom-economical means to synthesize α-branched amines. Prior examples featured symmetrical or electronically biased substrates. Here we report a controllable α-functionalization of amines in which regioselectivity can be tuned with minor changes to the reaction conditions.

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Regioselective, Photocatalytic α-Functionalization of Amines

Abstract

ASJC Scopus subject areas

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