Regulation of circadian rhythmicity

Joseph S. Takahashi, Martin Zatz

Research output: Contribution to journalArticle

220 Scopus citations

Abstract

Daily rhythms in many behavioral, physiological; and biochemical functions are generated by endogenous oscillators that function as internal 24-hour clocks. Under natural conditions, these oscillators are synchronized to the daily environmental cycle Of light and darkness. Recent advances in locating circadian pacemakers in the brain and in establishing model systems promise to Shed light on the cellular and biochemical mechanisms involved in the generation and regulation of circadian rhythms.

Original languageEnglish (US)
Pages (from-to)1104-1111
Number of pages8
JournalScience
Volume217
Issue number4565
DOIs
StatePublished - Jan 1 1982

ASJC Scopus subject areas

  • General

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