Regulation of signal transduction by endocytosis

Brian P. Ceresa, Sandra L. Schmid

Research output: Contribution to journalReview article

251 Scopus citations

Abstract

Endocytosis of ligand-activated receptors has generally been considered a mechanism to attenuate signaling. There is now a growing body of evidence suggesting that this process is much more sophisticated and that endocytic membrane trafficking regulates both the intensity of signaling and the colocalization of activated receptors with downstream signaling molecules.

Original languageEnglish (US)
Pages (from-to)204-210
Number of pages7
JournalCurrent Opinion in Cell Biology
Volume12
Issue number2
DOIs
StatePublished - Apr 1 2000

ASJC Scopus subject areas

  • Cell Biology

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