Regulatory mechanisms that coordinate skeletal muscle differentiation and cell cycle withdrawal

Andrew B. Lassar, Stephen X. Skapek, Bennett Novitch

Research output: Contribution to journalArticle

298 Scopus citations

Abstract

Skeletal muscle differentiation entails the coupling of muscle-specific gene expression to terminal withdrawal from the cell cycle. Several models have recently been proposed which attempt to explain how regulated expression and function of myogenic transcription factors ensures that proliferation and differentiation of skeletal muscle cells are mutually exclusive processes.

Original languageEnglish (US)
Pages (from-to)788-794
Number of pages7
JournalCurrent Opinion in Cell Biology
Volume6
Issue number6
DOIs
StatePublished - Dec 1994

ASJC Scopus subject areas

  • Cell Biology

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