Relation between arterial blood pressure and cerebral blood flow velocity in simulated sleep apnea

Gedaa Hassan, Raichel Alex, Gauri Bhave, Mohammad A. Al-Abed, Aditya Bashaboyina, Swathi Iyer, Donald E. Watenpaugh, Rong Zhang, Khosrow Behbehani

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Obstructive Sleep Apnea (OSA) is one of the most common breathing disorder, affecting approximately 27% of U.S. adults. Limited data have suggested that OSA causes cerebral autoregulation impairment, thus being an important risk factor to stroke. The objective of this paper is to investigate and measure the relation between arterial blood pressure (BP) and cerebral blood flow velocity (CBFV) in simulated apnea. Sixteen healthy subjects (9 male, 7 female) of 29±4.89 yrs age and body mass index of 24.07±4.84 kg/m2 participated in the study. Four protocols were used; sitting 30 seconds, 90s, and supine 30s and 90s. Our results showed that systolic BP and peak CBFV were correlated with average r=0.672 +0.265. Also, CBFV exhibited a significantly higher percent rise than BP. Thus, our findings suggest that cerebral autoregulation may be impaired during apnea episodes.

Original languageEnglish (US)
Title of host publicationProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Pages6349-6352
Number of pages4
DOIs
StatePublished - 2012
Event34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2012 - San Diego, CA, United States
Duration: Aug 28 2012Sep 1 2012

Other

Other34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2012
CountryUnited States
CitySan Diego, CA
Period8/28/129/1/12

Fingerprint

Cerebrovascular Circulation
Blood Flow Velocity
Blood pressure
Sleep Apnea Syndromes
Flow velocity
Arterial Pressure
Blood
Obstructive Sleep Apnea
Apnea
Blood Pressure
Homeostasis
Healthy Volunteers
Respiration
Body Mass Index
Stroke
Sleep

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

Cite this

Hassan, G., Alex, R., Bhave, G., Al-Abed, M. A., Bashaboyina, A., Iyer, S., ... Behbehani, K. (2012). Relation between arterial blood pressure and cerebral blood flow velocity in simulated sleep apnea. In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS (pp. 6349-6352). [6347446] https://doi.org/10.1109/EMBC.2012.6347446

Relation between arterial blood pressure and cerebral blood flow velocity in simulated sleep apnea. / Hassan, Gedaa; Alex, Raichel; Bhave, Gauri; Al-Abed, Mohammad A.; Bashaboyina, Aditya; Iyer, Swathi; Watenpaugh, Donald E.; Zhang, Rong; Behbehani, Khosrow.

Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. 2012. p. 6349-6352 6347446.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hassan, G, Alex, R, Bhave, G, Al-Abed, MA, Bashaboyina, A, Iyer, S, Watenpaugh, DE, Zhang, R & Behbehani, K 2012, Relation between arterial blood pressure and cerebral blood flow velocity in simulated sleep apnea. in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS., 6347446, pp. 6349-6352, 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2012, San Diego, CA, United States, 8/28/12. https://doi.org/10.1109/EMBC.2012.6347446
Hassan G, Alex R, Bhave G, Al-Abed MA, Bashaboyina A, Iyer S et al. Relation between arterial blood pressure and cerebral blood flow velocity in simulated sleep apnea. In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. 2012. p. 6349-6352. 6347446 https://doi.org/10.1109/EMBC.2012.6347446
Hassan, Gedaa ; Alex, Raichel ; Bhave, Gauri ; Al-Abed, Mohammad A. ; Bashaboyina, Aditya ; Iyer, Swathi ; Watenpaugh, Donald E. ; Zhang, Rong ; Behbehani, Khosrow. / Relation between arterial blood pressure and cerebral blood flow velocity in simulated sleep apnea. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. 2012. pp. 6349-6352
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