Relative effects of graft copolymer and polyamines on triplex stabilization under physiological conditions

A. Ferdous; H. Watanabe; T. Akaike; A. Maruyama

doi:10.1080/07328319908044811

Relative effects of graft copolymer and polyamines on triplex stabilization under physiological conditions

A. Ferdous, H. Watanabe, T. Akaike, A. Maruyama

Research output: Contribution to journal › Article › peer-review

Abstract

Triplex-stabilizing effect of a graft copolymer under physiologically relevant conditions has been evaluated and compared with other polyamines. Here we show that the graft copolymer significantly stabilizes triplex DNAs with amazingly higher efficacy than that of physiological concentrations of spermine and spermidine.

Original language	English (US)
Pages (from-to)	1651-1653
Number of pages	3
Journal	Nucleosides and Nucleotides
Volume	18
Issue number	6-7
DOIs	https://doi.org/10.1080/07328319908044811
State	Published - 1999

ASJC Scopus subject areas

Biochemistry
Genetics

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10.1080/07328319908044811

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title = "Relative effects of graft copolymer and polyamines on triplex stabilization under physiological conditions",

abstract = "Triplex-stabilizing effect of a graft copolymer under physiologically relevant conditions has been evaluated and compared with other polyamines. Here we show that the graft copolymer significantly stabilizes triplex DNAs with amazingly higher efficacy than that of physiological concentrations of spermine and spermidine.",

author = "A. Ferdous and H. Watanabe and T. Akaike and A. Maruyama",

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AU - Ferdous, A.

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AU - Akaike, T.

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PY - 1999

Y1 - 1999

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AB - Triplex-stabilizing effect of a graft copolymer under physiologically relevant conditions has been evaluated and compared with other polyamines. Here we show that the graft copolymer significantly stabilizes triplex DNAs with amazingly higher efficacy than that of physiological concentrations of spermine and spermidine.

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JO - Nucleosides and Nucleotides

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Relative effects of graft copolymer and polyamines on triplex stabilization under physiological conditions

Abstract

ASJC Scopus subject areas

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