Relative effects of graft copolymer and polyamines on triplex stabilization under physiological conditions

A. Ferdous, H. Watanabe, T. Akaike, A. Maruyama

Research output: Contribution to journalArticle

Abstract

Triplex-stabilizing effect of a graft copolymer under physiologically relevant conditions has been evaluated and compared with other polyamines. Here we show that the graft copolymer significantly stabilizes triplex DNAs with amazingly higher efficacy than that of physiological concentrations of spermine and spermidine.

Original languageEnglish (US)
Pages (from-to)1651-1653
Number of pages3
JournalNucleosides and Nucleotides
Volume18
Issue number6-7
StatePublished - 1999

Fingerprint

Graft copolymers
Polyamines
Stabilization
Transplants
Spermidine
Spermine
triplex DNA

ASJC Scopus subject areas

  • Biochemistry
  • Genetics

Cite this

Relative effects of graft copolymer and polyamines on triplex stabilization under physiological conditions. / Ferdous, A.; Watanabe, H.; Akaike, T.; Maruyama, A.

In: Nucleosides and Nucleotides, Vol. 18, No. 6-7, 1999, p. 1651-1653.

Research output: Contribution to journalArticle

@article{4d9d5d526efd489ca5e040ab2c21a9b6,
title = "Relative effects of graft copolymer and polyamines on triplex stabilization under physiological conditions",
abstract = "Triplex-stabilizing effect of a graft copolymer under physiologically relevant conditions has been evaluated and compared with other polyamines. Here we show that the graft copolymer significantly stabilizes triplex DNAs with amazingly higher efficacy than that of physiological concentrations of spermine and spermidine.",
author = "A. Ferdous and H. Watanabe and T. Akaike and A. Maruyama",
year = "1999",
language = "English (US)",
volume = "18",
pages = "1651--1653",
journal = "Nucleosides and Nucleotides",
issn = "0732-8311",
publisher = "Taylor and Francis Ltd.",
number = "6-7",

}

TY - JOUR

T1 - Relative effects of graft copolymer and polyamines on triplex stabilization under physiological conditions

AU - Ferdous, A.

AU - Watanabe, H.

AU - Akaike, T.

AU - Maruyama, A.

PY - 1999

Y1 - 1999

N2 - Triplex-stabilizing effect of a graft copolymer under physiologically relevant conditions has been evaluated and compared with other polyamines. Here we show that the graft copolymer significantly stabilizes triplex DNAs with amazingly higher efficacy than that of physiological concentrations of spermine and spermidine.

AB - Triplex-stabilizing effect of a graft copolymer under physiologically relevant conditions has been evaluated and compared with other polyamines. Here we show that the graft copolymer significantly stabilizes triplex DNAs with amazingly higher efficacy than that of physiological concentrations of spermine and spermidine.

UR - http://www.scopus.com/inward/record.url?scp=0032781716&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032781716&partnerID=8YFLogxK

M3 - Article

VL - 18

SP - 1651

EP - 1653

JO - Nucleosides and Nucleotides

JF - Nucleosides and Nucleotides

SN - 0732-8311

IS - 6-7

ER -