Relative effects of graft copolymer and polyamines on triplex stabilization under physiological conditions

A. Ferdous, H. Watanabe, T. Akaike, A. Maruyama

Research output: Contribution to journalArticle

Abstract

Triplex-stabilizing effect of a graft copolymer under physiologically relevant conditions has been evaluated and compared with other polyamines. Here we show that the graft copolymer significantly stabilizes triplex DNAs with amazingly higher efficacy than that of physiological concentrations of spermine and spermidine.

Original languageEnglish (US)
Pages (from-to)1651-1653
Number of pages3
JournalNucleosides and Nucleotides
Volume18
Issue number6-7
DOIs
StatePublished - Jan 1 1999

ASJC Scopus subject areas

  • Biochemistry
  • Genetics

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