Abstract
Synthetic TRF (pyroglutamylhistidyl-proline amide) was infused (1 ng/min) for 20 min (1) into the anterior pituitary of 10 rats by way of a cannulated hypophysial stalk portal vessel or (2) into a femoral vein of 10 rats. At the end of the 20-min infusion period, the plasma concentration of TSH in 8 of 10 rats given TRF via a cannulated portal vessel was significantly greater than the pre-infusion level. In contrast, in only 3 of 10 rats given TRF via a femoral vein was the plasma concentration of TSH significantly greater than the pre-infusion level of TSH.
Original language | English (US) |
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Pages (from-to) | 1054-1056 |
Number of pages | 3 |
Journal | Endocrinology |
Volume | 89 |
Issue number | 4 |
DOIs | |
State | Published - Oct 1971 |
ASJC Scopus subject areas
- Endocrinology