Remote vascular catastrophes after neurovascular interventional therapy for type 4 Ehlers-Danlos syndrome

Michael B. Horowitz, Phillip D. Purdy, R. James Valentine, Kevin Morrill

Research output: Contribution to journalArticle

50 Scopus citations


Type 4 Ehlers-Danlos Syndrome (EDS 4) is the most malignant form of Ehlers-Danlos Syndrome, often accompanied by neurovascular complications secondary to vessel dissection or aneurysms. The fragile nature of connective tissue in these patients makes exovascular and endovascular treatment hazardous. We have treated four patients with EDS 4 over the last 8 years by using neuroendovascular procedures. Two of these individuals suffered remote vascular injuries around the time of their procedures and ultimately died. The circumstances surrounding their deaths will make up the body of this report.

Original languageEnglish (US)
Pages (from-to)974-976
Number of pages3
JournalAmerican Journal of Neuroradiology
Issue number5
StatePublished - May 25 2000


ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

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