Renal imaging studies at 1.5 and 9.4 T: Effects of diuretics

S. K. Sarkar, G. A. Holland, R. E. Lenkinski, M. A. Mattingly, L. B. Kinter

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

We have studied the effects of two diuretics, selective for renal cortical (furosemide) and inner medullary (vasopressin antagonist) water handling, in rat kidney at 1.5 T and find that furosmide completely dissipates the cortical‐inner medullary T2 gradient whereas the vasopressin antagonist has little effect. This phenomenon appears to be related to changes in luminal water content. We also demonstrate the feasibility of obtaining live mouse kidney images with a resolution of 100 × 100 × 700 μm at 9.4 T. © 1988 Academic Press, Inc.

Original languageEnglish (US)
Pages (from-to)117-124
Number of pages8
JournalMagnetic resonance in medicine
Volume7
Issue number1
DOIs
StatePublished - May 1988

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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