Repigmentation in vitiligo: position paper of the Vitiligo Global Issues Consensus Conference

the VGICC

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

The Vitiligo Global Issues Consensus Conference (VGICC), through an international e-Delphi consensus, concluded that ‘repigmentation’ and ‘maintenance of gained repigmentation’ are essential core outcome measures in future vitiligo trials. This VGICC position paper addresses these core topics in two sections and includes an atlas depicting vitiligo repigmentation patterns and color match. The first section delineates mechanisms and characteristics of vitiligo repigmentation, and the second section summarizes the outcomes of international meeting discussions and two e-surveys on vitiligo repigmentation, which had been carried out over 3 yr. Treatment is defined as successful if repigmentation exceeds 80% and at least 80% of the gained repigmentation is maintained for over 6 months. No agreement was found on the best outcome measure for assessing target or global repigmentation, therefore highlighting the limitations of e-surveys in addressing clinical measurements. Until there is a clear consensus, existing tools should be selected according to the specific needs of each study. A workshop will be conducted to address the remaining issues so as to achieve a consensus.

Original languageEnglish (US)
Pages (from-to)28-40
Number of pages13
JournalPigment Cell and Melanoma Research
Volume30
Issue number1
DOIs
StatePublished - Jan 1 2017

Keywords

  • outcome measure
  • pigment
  • repigmentation
  • repigmentation pattern
  • vitiligo

ASJC Scopus subject areas

  • Oncology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Dermatology

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