Research and therapeutics-traditional and emerging therapies in systemic lupus erythematosus

Laurie S. Davis, Andreas M. Reimold

Research output: Contribution to journalReview articlepeer-review

19 Scopus citations

Abstract

This review summarizes traditional and emerging therapies for SLE. Evidence suggests that the heterogeneity of SLE is a crucial aspect contributing to the failure of large clinical trials for new targeted therapies. A clearer understanding of the mechanisms driving disease pathogenesis combined with recent advances in medical science are predicted to enable accelerated progress towards improved SLE diagnosis and personalized approaches to treatment.

Original languageEnglish (US)
Pages (from-to)I100-I113
JournalRheumatology (United Kingdom)
Volume56
DOIs
StatePublished - Apr 2017

Keywords

  • B cells
  • Biological therapies
  • Clinical trials
  • Immunotherapy
  • Methods
  • Systemic lupus erythematosus and autoimmunity

ASJC Scopus subject areas

  • Rheumatology
  • Pharmacology (medical)

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