Research and therapeutics-traditional and emerging therapies in systemic lupus erythematosus

Laurie S. Davis; Andreas M. Reimold

doi:10.1093/rheumatology/kew417

Research and therapeutics-traditional and emerging therapies in systemic lupus erythematosus

Laurie S. Davis, Andreas M. Reimold

Research output: Contribution to journal › Review article › peer-review

40 Scopus citations

Abstract

This review summarizes traditional and emerging therapies for SLE. Evidence suggests that the heterogeneity of SLE is a crucial aspect contributing to the failure of large clinical trials for new targeted therapies. A clearer understanding of the mechanisms driving disease pathogenesis combined with recent advances in medical science are predicted to enable accelerated progress towards improved SLE diagnosis and personalized approaches to treatment.

Original language	English (US)
Pages (from-to)	I100-I113
Journal	Rheumatology (United Kingdom)
Volume	56
DOIs	https://doi.org/10.1093/rheumatology/kew417
State	Published - Apr 2017

Keywords

B cells
Biological therapies
Clinical trials
Immunotherapy
Methods
Systemic lupus erythematosus and autoimmunity

ASJC Scopus subject areas

Rheumatology
Pharmacology (medical)

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10.1093/rheumatology/kew417

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title = "Research and therapeutics-traditional and emerging therapies in systemic lupus erythematosus",

abstract = "This review summarizes traditional and emerging therapies for SLE. Evidence suggests that the heterogeneity of SLE is a crucial aspect contributing to the failure of large clinical trials for new targeted therapies. A clearer understanding of the mechanisms driving disease pathogenesis combined with recent advances in medical science are predicted to enable accelerated progress towards improved SLE diagnosis and personalized approaches to treatment.",

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AB - This review summarizes traditional and emerging therapies for SLE. Evidence suggests that the heterogeneity of SLE is a crucial aspect contributing to the failure of large clinical trials for new targeted therapies. A clearer understanding of the mechanisms driving disease pathogenesis combined with recent advances in medical science are predicted to enable accelerated progress towards improved SLE diagnosis and personalized approaches to treatment.

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KW - Methods

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Research and therapeutics-traditional and emerging therapies in systemic lupus erythematosus

Abstract

Keywords

ASJC Scopus subject areas

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