Resistant hypertension

Norman M Kaplan

Research output: Contribution to journalArticle

92 Scopus citations


Hypertension that remains above 140/90 mmHg despite the use of three antihypertensive drugs in a rational combination at full doses and including a diuretic is known as 'resistant'. The percentage of hypertensives whose condition is resistant varies in large part upon the setting: those seen in general practice show a prevalence of perhaps 5%; those seen by nephrologists, probably 50%. This paper reviews the major causes of resistant hypertension and provides specific recommendations for the evaluation and management of patients with this threatening condition.

Original languageEnglish (US)
Pages (from-to)1441-1444
Number of pages4
JournalJournal of Hypertension
Issue number8
Publication statusPublished - Aug 2005



  • Resistant hypertension

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology

Cite this

Kaplan, N. M. (2005). Resistant hypertension. Journal of Hypertension, 23(8), 1441-1444.