Responses of muscle sympathetic nerve activity to static handgrip exercise after 14 days of exposure to simulated microgravity.

D. Michikami, A. Kamiya, Q. Fu, J. Cui, H. Usui, S. Atsuta, Y. Niimi, S. Iwase, T. Mano

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Decrease in muscle perfusion affects on cardiovascular response to exercise. Muscle hypoperfusion enhances the increase in blood pressure responses to exercise. Muscle perfusion depends not only on central blood pressure but also how fit the active muscle is above or below the heart level; muscle perfusion decreases as arm is elevated. Static exercise increases muscle sympathetic nerve activity (MSNA) innervating vessels in non-active muscles. The exercise-induced increase in MSNA is mainly mediated by stimulating chemosensitive muscle afferents in active muscles. However, the effect of arm elevation on MSNA during forearm exercise is not examined. On the other hand, space flight and simulated microgravity exposure causes reduction in muscle blood flow, suggesting chronic muscle hypoperfused condition during simulated microgravity. Therefore, there is a possibility that arm elevation after microgravity exposure alters MSNA responsiveness during exercise. However, arm elevation effect after exposure to simulated microgravity is not examined.

Original languageEnglish (US)
JournalJournal of gravitational physiology : a journal of the International Society for Gravitational Physiology
Volume7
Issue number2
StatePublished - 2000

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Weightlessness
Muscles
Arm
Perfusion
Blood Pressure
Space Flight
Forearm

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Responses of muscle sympathetic nerve activity to static handgrip exercise after 14 days of exposure to simulated microgravity. / Michikami, D.; Kamiya, A.; Fu, Q.; Cui, J.; Usui, H.; Atsuta, S.; Niimi, Y.; Iwase, S.; Mano, T.

In: Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology, Vol. 7, No. 2, 2000.

Research output: Contribution to journalArticle

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AU - Cui, J.

AU - Usui, H.

AU - Atsuta, S.

AU - Niimi, Y.

AU - Iwase, S.

AU - Mano, T.

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