Rest-activity cycles in childhood and adolescent depression

Roseanne Armitage, Robert Hoffmann, Graham Emslie, Jeanne Rintelman, Jarrette Moore, Kelly Lewis

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

Objective: To quantify circadian rhythms in rest-activity cycles in depressed children and adolescents. Method. Rest-activity cycles were evaluated by actigraphy over five consecutive 24-hour periods in 100 children and adolescents, including 59 outpatients with major depressive disorder (MDD) and 41 healthy normal controls. Total activity, total light exposure, and time spent in light at more than 1,000 lux were averaged over the recording period for each participant. Time series analysis was used to determine the amplitude and period length of circadian rhythms in rest-activity. Results: Overall, adolescents with MDD had lower activity levels, damped circadian amplitude, and lower light exposure and spent less time in bright light than healthy controls. Among children, those with MDD showed lower light exposure and spent less time in bright light, but only depressed girls showed damped circadian amplitude. The sex differences were substantially greater in the MDD group than in the normal control group. Conclusions: These results confirm damped circadian rhythms in children and adolescents with MDD and highlight the influence of gender and age on these measures.

Original languageEnglish (US)
Pages (from-to)761-769
Number of pages9
JournalJournal of the American Academy of Child and Adolescent Psychiatry
Volume43
Issue number6
DOIs
StatePublished - Jun 2004

Fingerprint

Activity Cycles
Major Depressive Disorder
Depression
Light
Circadian Rhythm
Actigraphy
Sex Characteristics
Outpatients
Control Groups

Keywords

  • Childhood depression
  • Circadian rhythms
  • Gender
  • Rest-activity cycles

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Developmental and Educational Psychology

Cite this

Rest-activity cycles in childhood and adolescent depression. / Armitage, Roseanne; Hoffmann, Robert; Emslie, Graham; Rintelman, Jeanne; Moore, Jarrette; Lewis, Kelly.

In: Journal of the American Academy of Child and Adolescent Psychiatry, Vol. 43, No. 6, 06.2004, p. 761-769.

Research output: Contribution to journalArticle

Armitage, Roseanne ; Hoffmann, Robert ; Emslie, Graham ; Rintelman, Jeanne ; Moore, Jarrette ; Lewis, Kelly. / Rest-activity cycles in childhood and adolescent depression. In: Journal of the American Academy of Child and Adolescent Psychiatry. 2004 ; Vol. 43, No. 6. pp. 761-769.
@article{a7b661e580ab4004a6b8ced74d637d7d,
title = "Rest-activity cycles in childhood and adolescent depression",
abstract = "Objective: To quantify circadian rhythms in rest-activity cycles in depressed children and adolescents. Method. Rest-activity cycles were evaluated by actigraphy over five consecutive 24-hour periods in 100 children and adolescents, including 59 outpatients with major depressive disorder (MDD) and 41 healthy normal controls. Total activity, total light exposure, and time spent in light at more than 1,000 lux were averaged over the recording period for each participant. Time series analysis was used to determine the amplitude and period length of circadian rhythms in rest-activity. Results: Overall, adolescents with MDD had lower activity levels, damped circadian amplitude, and lower light exposure and spent less time in bright light than healthy controls. Among children, those with MDD showed lower light exposure and spent less time in bright light, but only depressed girls showed damped circadian amplitude. The sex differences were substantially greater in the MDD group than in the normal control group. Conclusions: These results confirm damped circadian rhythms in children and adolescents with MDD and highlight the influence of gender and age on these measures.",
keywords = "Childhood depression, Circadian rhythms, Gender, Rest-activity cycles",
author = "Roseanne Armitage and Robert Hoffmann and Graham Emslie and Jeanne Rintelman and Jarrette Moore and Kelly Lewis",
year = "2004",
month = "6",
doi = "10.1097/01.chi.0000122731.72597.4e",
language = "English (US)",
volume = "43",
pages = "761--769",
journal = "Journal of the American Academy of Child and Adolescent Psychiatry",
issn = "0890-8567",
publisher = "Elsevier Limited",
number = "6",

}

TY - JOUR

T1 - Rest-activity cycles in childhood and adolescent depression

AU - Armitage, Roseanne

AU - Hoffmann, Robert

AU - Emslie, Graham

AU - Rintelman, Jeanne

AU - Moore, Jarrette

AU - Lewis, Kelly

PY - 2004/6

Y1 - 2004/6

N2 - Objective: To quantify circadian rhythms in rest-activity cycles in depressed children and adolescents. Method. Rest-activity cycles were evaluated by actigraphy over five consecutive 24-hour periods in 100 children and adolescents, including 59 outpatients with major depressive disorder (MDD) and 41 healthy normal controls. Total activity, total light exposure, and time spent in light at more than 1,000 lux were averaged over the recording period for each participant. Time series analysis was used to determine the amplitude and period length of circadian rhythms in rest-activity. Results: Overall, adolescents with MDD had lower activity levels, damped circadian amplitude, and lower light exposure and spent less time in bright light than healthy controls. Among children, those with MDD showed lower light exposure and spent less time in bright light, but only depressed girls showed damped circadian amplitude. The sex differences were substantially greater in the MDD group than in the normal control group. Conclusions: These results confirm damped circadian rhythms in children and adolescents with MDD and highlight the influence of gender and age on these measures.

AB - Objective: To quantify circadian rhythms in rest-activity cycles in depressed children and adolescents. Method. Rest-activity cycles were evaluated by actigraphy over five consecutive 24-hour periods in 100 children and adolescents, including 59 outpatients with major depressive disorder (MDD) and 41 healthy normal controls. Total activity, total light exposure, and time spent in light at more than 1,000 lux were averaged over the recording period for each participant. Time series analysis was used to determine the amplitude and period length of circadian rhythms in rest-activity. Results: Overall, adolescents with MDD had lower activity levels, damped circadian amplitude, and lower light exposure and spent less time in bright light than healthy controls. Among children, those with MDD showed lower light exposure and spent less time in bright light, but only depressed girls showed damped circadian amplitude. The sex differences were substantially greater in the MDD group than in the normal control group. Conclusions: These results confirm damped circadian rhythms in children and adolescents with MDD and highlight the influence of gender and age on these measures.

KW - Childhood depression

KW - Circadian rhythms

KW - Gender

KW - Rest-activity cycles

UR - http://www.scopus.com/inward/record.url?scp=2942702331&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=2942702331&partnerID=8YFLogxK

U2 - 10.1097/01.chi.0000122731.72597.4e

DO - 10.1097/01.chi.0000122731.72597.4e

M3 - Article

C2 - 15167093

AN - SCOPUS:2942702331

VL - 43

SP - 761

EP - 769

JO - Journal of the American Academy of Child and Adolescent Psychiatry

JF - Journal of the American Academy of Child and Adolescent Psychiatry

SN - 0890-8567

IS - 6

ER -