Restoration of the coagulation cascade on CPB: A case report

K. J. Lilly, P. A. Pirundini, A. A. Fox, S. C. Body, C. Shaw, R. J. Rizzo

Research output: Contribution to journalArticle

Abstract

Coagulopathy can sometimes be observed when CPB times are prolonged. Correction of coagulopathy post CPB can present the surgical team with a number of challenges, including right ventricular volume overload, hemodilution, anemia and excessive cell salvage with further loss of coagulation factors. Restoration of the coagulation cascade on CPB may help to avoid these issues. This case report is of a 64-year-old male with a delayed diagnosis of aortic dissection. The patient presented to the cardiac surgery operating room with hepatic and renal shock/failure, with the resulting coagulopathy. The described technique is representative of a technique that we sometimes employ to restore the clotting mechanism before separating from bypass.

Original languageEnglish (US)
Pages (from-to)272-274
Number of pages3
JournalPerfusion (United Kingdom)
Volume29
Issue number3
DOIs
StatePublished - 2014

Fingerprint

Hemodilution
Blood Coagulation Factors
Delayed Diagnosis
Operating Rooms
Coagulation
restoration
surgery
Thoracic Surgery
Restoration
Renal Insufficiency
Dissection
Anemia
Shock
Operating rooms
Salvaging
Liver
Surgery
time

Keywords

  • ACT decoupling: hemoconcentration
  • coagulopathy
  • fresh frozen plasma (FFP)

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging
  • Advanced and Specialized Nursing
  • Safety Research
  • Medicine(all)

Cite this

Lilly, K. J., Pirundini, P. A., Fox, A. A., Body, S. C., Shaw, C., & Rizzo, R. J. (2014). Restoration of the coagulation cascade on CPB: A case report. Perfusion (United Kingdom), 29(3), 272-274. https://doi.org/10.1177/0267659113507471

Restoration of the coagulation cascade on CPB : A case report. / Lilly, K. J.; Pirundini, P. A.; Fox, A. A.; Body, S. C.; Shaw, C.; Rizzo, R. J.

In: Perfusion (United Kingdom), Vol. 29, No. 3, 2014, p. 272-274.

Research output: Contribution to journalArticle

Lilly, KJ, Pirundini, PA, Fox, AA, Body, SC, Shaw, C & Rizzo, RJ 2014, 'Restoration of the coagulation cascade on CPB: A case report', Perfusion (United Kingdom), vol. 29, no. 3, pp. 272-274. https://doi.org/10.1177/0267659113507471
Lilly, K. J. ; Pirundini, P. A. ; Fox, A. A. ; Body, S. C. ; Shaw, C. ; Rizzo, R. J. / Restoration of the coagulation cascade on CPB : A case report. In: Perfusion (United Kingdom). 2014 ; Vol. 29, No. 3. pp. 272-274.
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