Retrospective cohort study of surgical staging for ovarian low malignant potential tumors

Shana N. Wingo, Lynne M. Knowles, Kelley S. Carrick, David S. Miller, John O. Schorge

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

Objective: The purpose of this study was to determine the benefit of surgically staging ovarian low malignant potential tumors. Study design: This was a retrospective cohort study of all ovarian low malignant potential tumors that were diagnosed by frozen section or final pathologic review from 2003 to 2005. Results: Twenty-two of 32 patients (69%) were staged surgically. Sixteen low malignant potential tumors were stage I by final pathologic review, and 4 tumors were upstaged to stage II-III disease. Two other patients had early invasive ovarian carcinoma, despite a frozen section that suggested low malignant potential; 1 patient received adjuvant chemotherapy. The tumors of 10 women (31%) were unstaged. Frozen section suspicion of low malignant potential (P = .003) and surgery by a gynecologic oncologist (P < .001) correlated with staging. Preoperative CA-125, intraoperative blood loss, and postoperative hospitalization were increased in patients with staged disease (each P < .05). Two women who underwent fertility-sparing surgery experienced a recurrence in the contralateral ovary. Conclusion: Surgical staging of ovarian low malignant potential tumors has limited value for most patients, unless invasive carcinoma is diagnosed by final pathologic review.

Original languageEnglish (US)
Pages (from-to)e20-e22
JournalAmerican journal of obstetrics and gynecology
Volume194
Issue number5
DOIs
StatePublished - May 1 2006

Keywords

  • Borderline ovarian tumors
  • Ovarian low malignant potential tumors
  • Surgical staging

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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