Reversal of perfusion and diffusion abnormalities after intravenous thrombolysis for a lacunar infarction

Julio A. Chalela, Mustapha Ezzeddine, Lawrence Latour, Steven Warach

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Perfusion and diffusion magnetic resonance imaging (MRI) have been used to guide therapy in patients with large vessel occlusions. In an analogous fashion, the authors used perfusion and diffusion MRI to demonstrate a perfusion deficit and a matching diffusion lesion in a patient with lacunar infarct. Following thrombolytic therapy, the authors observed a reversal of the perfusion deficit, the diffusion lesion, and clinical recovery. This case suggests that perfusion and diffusion MRI may be informative in patients with lacunar infarction who are candidates for thrombolysis.

Original languageEnglish (US)
Pages (from-to)152-154
Number of pages3
JournalJournal of Neuroimaging
Volume13
Issue number2
DOIs
StatePublished - Apr 2003

Fingerprint

Lacunar Stroke
Diffusion Magnetic Resonance Imaging
Magnetic Resonance Angiography
Perfusion
Thrombolytic Therapy
Therapeutics

Keywords

  • DWI lesion reversal
  • Lacunar infarct
  • Thrombolysis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology
  • Neuroscience(all)
  • Radiological and Ultrasound Technology

Cite this

Reversal of perfusion and diffusion abnormalities after intravenous thrombolysis for a lacunar infarction. / Chalela, Julio A.; Ezzeddine, Mustapha; Latour, Lawrence; Warach, Steven.

In: Journal of Neuroimaging, Vol. 13, No. 2, 04.2003, p. 152-154.

Research output: Contribution to journalArticle

Chalela, Julio A. ; Ezzeddine, Mustapha ; Latour, Lawrence ; Warach, Steven. / Reversal of perfusion and diffusion abnormalities after intravenous thrombolysis for a lacunar infarction. In: Journal of Neuroimaging. 2003 ; Vol. 13, No. 2. pp. 152-154.
@article{442e539f75c04a9e8aa9784d9f26e22e,
title = "Reversal of perfusion and diffusion abnormalities after intravenous thrombolysis for a lacunar infarction",
abstract = "Perfusion and diffusion magnetic resonance imaging (MRI) have been used to guide therapy in patients with large vessel occlusions. In an analogous fashion, the authors used perfusion and diffusion MRI to demonstrate a perfusion deficit and a matching diffusion lesion in a patient with lacunar infarct. Following thrombolytic therapy, the authors observed a reversal of the perfusion deficit, the diffusion lesion, and clinical recovery. This case suggests that perfusion and diffusion MRI may be informative in patients with lacunar infarction who are candidates for thrombolysis.",
keywords = "DWI lesion reversal, Lacunar infarct, Thrombolysis",
author = "Chalela, {Julio A.} and Mustapha Ezzeddine and Lawrence Latour and Steven Warach",
year = "2003",
month = "4",
doi = "10.1177/1051228403251260",
language = "English (US)",
volume = "13",
pages = "152--154",
journal = "Journal of Neuroimaging",
issn = "1051-2284",
publisher = "Wiley-Blackwell",
number = "2",

}

TY - JOUR

T1 - Reversal of perfusion and diffusion abnormalities after intravenous thrombolysis for a lacunar infarction

AU - Chalela, Julio A.

AU - Ezzeddine, Mustapha

AU - Latour, Lawrence

AU - Warach, Steven

PY - 2003/4

Y1 - 2003/4

N2 - Perfusion and diffusion magnetic resonance imaging (MRI) have been used to guide therapy in patients with large vessel occlusions. In an analogous fashion, the authors used perfusion and diffusion MRI to demonstrate a perfusion deficit and a matching diffusion lesion in a patient with lacunar infarct. Following thrombolytic therapy, the authors observed a reversal of the perfusion deficit, the diffusion lesion, and clinical recovery. This case suggests that perfusion and diffusion MRI may be informative in patients with lacunar infarction who are candidates for thrombolysis.

AB - Perfusion and diffusion magnetic resonance imaging (MRI) have been used to guide therapy in patients with large vessel occlusions. In an analogous fashion, the authors used perfusion and diffusion MRI to demonstrate a perfusion deficit and a matching diffusion lesion in a patient with lacunar infarct. Following thrombolytic therapy, the authors observed a reversal of the perfusion deficit, the diffusion lesion, and clinical recovery. This case suggests that perfusion and diffusion MRI may be informative in patients with lacunar infarction who are candidates for thrombolysis.

KW - DWI lesion reversal

KW - Lacunar infarct

KW - Thrombolysis

UR - http://www.scopus.com/inward/record.url?scp=0037380249&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037380249&partnerID=8YFLogxK

U2 - 10.1177/1051228403251260

DO - 10.1177/1051228403251260

M3 - Article

C2 - 12722498

AN - SCOPUS:0037380249

VL - 13

SP - 152

EP - 154

JO - Journal of Neuroimaging

JF - Journal of Neuroimaging

SN - 1051-2284

IS - 2

ER -