Reversible Monoubiquitination of PCNA: A Novel Slant on Regulating Translesion DNA Synthesis

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Deubiquitination of monoubiquitinated proteins is effected by a large number of deubiquitinating enzymes (DUBs) that function as cysteine proteases in eukaryotic cells. Huang et al. (2006) report the regulation of monoubiquitination of PCNA by autocleavage of a DUB called USP1 in cells exposed to UV radiation.

Original languageEnglish (US)
Pages (from-to)150-152
Number of pages3
JournalMolecular Cell
Issue number2
Publication statusPublished - Apr 21 2006


ASJC Scopus subject areas

  • Molecular Biology

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