Review article: Helicobacter pylori and gastric adenocarcinoma

W. L. Peterson

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations

Abstract

Gastric adenocarcinoma is still the second most common cause of death from cancer, even though it is on the decline in developed countries. Although H. pylori gastritis appears to be a necessary antecedent to the development of gastric adenocarcinoma, it is not a sufficient factor in and of itself. Other required factors for the progression of this disease are poorly understood. Patients with antral predominant gastritis seem protected from the disease, while patients with pangastritis are predisposed to both diffuse- and intestinal-type adenocarcinoma. Development of a vaccine against H. pylori might yield promising results in decreasing the incidence of gastric adenocarcinoma.

Original languageEnglish (US)
Pages (from-to)40-46
Number of pages7
JournalAlimentary Pharmacology and Therapeutics, Supplement
Volume16
Issue number1
StatePublished - Mar 1 2002

ASJC Scopus subject areas

  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Pharmacology (medical)

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