Review of acute kidney injury and continuous renal replacement therapy in pediatric extracorporeal membrane oxygenation

Christopher Jenks, Lakshmi Raman, Archana Dhar

Research output: Contribution to journalReview articlepeer-review

Abstract

Purpose: To review the relevant literature of acute kidney injury (AKI) and continuous renal replacement therapy (CRRT) as it relates to pediatric extracorporeal membrane oxygenation (ECMO). Methods: Available online relevant literature. Results: ECMO is a therapeutic modality utilized to support patients with refractory respiratory and/or cardiac failure. AKI and fluid overload (FO) are frequently observed in this patient population. There are multiple modalities that can be utilized for AKI and FO which include the following: diuretics, in-line hemofiltration, and CRRT. There are multiple considerations when using CRRT with ECMO including access, CRRT flows, hemolysis, anticoagulation, and CRRT termination. Conclusion: While each ECMO center has its own set of equipment, experiences, and practices, it is imperative that the international ECMO community continues to work together to provide an evidence-based approach to address the morbidity and mortality associated with AKI and FO.

Original languageEnglish (US)
Pages (from-to)254-260
Number of pages7
JournalIndian Journal of Thoracic and Cardiovascular Surgery
Volume37
DOIs
StatePublished - Apr 2021

Keywords

  • AKI
  • CRRT
  • ECLS
  • ECMO
  • Fluid overload

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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