Rheumatoid Arthritis: Early Diagnosis and Treatment

John J. Cush

Research output: Contribution to journalReview articlepeer-review

22 Scopus citations


Rheumatoid arthritis (RA) is a chronic, progressive inflammatory disorder that manifests as a symmetric polyarthritis of small and large joints that may lead to joint and periarticular structural damage and the consequences of systemic inflammation. This overview of early RA examines the unmet needs and challenges in RA, how to best diagnose RA, and pitfalls in early diagnosis and treatment. The rules for referral to a rheumatologist are reviewed. Primary care physicians are at the front line of early diagnosis and need to start disease-modifying therapy as soon as a diagnosis of RA is established.

Original languageEnglish (US)
Pages (from-to)355-365
Number of pages11
JournalMedical Clinics of North America
Issue number2
StatePublished - Mar 2021
Externally publishedYes


  • Early rheumatoid arthritis
  • Referral
  • Rheumatoid factor

ASJC Scopus subject areas

  • Medicine(all)


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