Rhodium-catalyzed annulation of N-benzoylsulfonamide with isocyanide through C-H activation

Chen Zhu, Weiqing Xie, J R Falck

Research output: Contribution to journalArticle

123 Citations (Scopus)

Abstract

The first rhodium-catalyzed annulation of N-benzoylsulfonamide (1) with isocyanide (2) through CiH activation is described. The transformation is broadly compatible with N-benzoylsulfonamides as well as isocyanides with different electronic properties. From a practical point of view, this method provides the most straightforward approach to a series of 3-(imino) isoindolinones (3). Ts=4-toluenesulfonyl.

Original languageEnglish (US)
Pages (from-to)12591-12595
Number of pages5
JournalChemistry - A European Journal
Volume17
Issue number45
DOIs
StatePublished - Nov 4 2011

Fingerprint

Rhodium
Cyanides
Electronic properties
Chemical activation

Keywords

  • annulations
  • CiH activation
  • heterocycles
  • isocyanide
  • rhodium

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Rhodium-catalyzed annulation of N-benzoylsulfonamide with isocyanide through C-H activation. / Zhu, Chen; Xie, Weiqing; Falck, J R.

In: Chemistry - A European Journal, Vol. 17, No. 45, 04.11.2011, p. 12591-12595.

Research output: Contribution to journalArticle

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