Rhodium-catalyzed annulation of N-benzoylsulfonamide with isocyanide through C-H activation

Chen Zhu; Weiqing Xie; J R Falck

doi:10.1002/chem.201102475

Rhodium-catalyzed annulation of N-benzoylsulfonamide with isocyanide through C-H activation

Chen Zhu, Weiqing Xie, J R Falck

Biochemistry

Research output: Contribution to journal › Article › peer-review

138 Scopus citations

Abstract

The first rhodium-catalyzed annulation of N-benzoylsulfonamide (1) with isocyanide (2) through CiH activation is described. The transformation is broadly compatible with N-benzoylsulfonamides as well as isocyanides with different electronic properties. From a practical point of view, this method provides the most straightforward approach to a series of 3-(imino) isoindolinones (3). Ts=4-toluenesulfonyl.

Original language	English (US)
Pages (from-to)	12591-12595
Number of pages	5
Journal	Chemistry - A European Journal
Volume	17
Issue number	45
DOIs	https://doi.org/10.1002/chem.201102475
State	Published - Nov 4 2011

Keywords

CiH activation
annulations
heterocycles
isocyanide
rhodium

ASJC Scopus subject areas

General Chemistry
Catalysis
Organic Chemistry

Access to Document

10.1002/chem.201102475

Cite this

@article{0357197648f64ef0a6f3f6f3cdf86791,

title = "Rhodium-catalyzed annulation of N-benzoylsulfonamide with isocyanide through C-H activation",

abstract = "The first rhodium-catalyzed annulation of N-benzoylsulfonamide (1) with isocyanide (2) through CiH activation is described. The transformation is broadly compatible with N-benzoylsulfonamides as well as isocyanides with different electronic properties. From a practical point of view, this method provides the most straightforward approach to a series of 3-(imino) isoindolinones (3). Ts=4-toluenesulfonyl.",

keywords = "CiH activation, annulations, heterocycles, isocyanide, rhodium",

author = "Chen Zhu and Weiqing Xie and Falck, {J R}",

year = "2011",

month = nov,

day = "4",

doi = "10.1002/chem.201102475",

language = "English (US)",

volume = "17",

pages = "12591--12595",

journal = "Chemistry - A European Journal",

issn = "0947-6539",

publisher = "Wiley-VCH Verlag",

number = "45",

}

TY - JOUR

T1 - Rhodium-catalyzed annulation of N-benzoylsulfonamide with isocyanide through C-H activation

AU - Zhu, Chen

AU - Xie, Weiqing

AU - Falck, J R

PY - 2011/11/4

Y1 - 2011/11/4

N2 - The first rhodium-catalyzed annulation of N-benzoylsulfonamide (1) with isocyanide (2) through CiH activation is described. The transformation is broadly compatible with N-benzoylsulfonamides as well as isocyanides with different electronic properties. From a practical point of view, this method provides the most straightforward approach to a series of 3-(imino) isoindolinones (3). Ts=4-toluenesulfonyl.

AB - The first rhodium-catalyzed annulation of N-benzoylsulfonamide (1) with isocyanide (2) through CiH activation is described. The transformation is broadly compatible with N-benzoylsulfonamides as well as isocyanides with different electronic properties. From a practical point of view, this method provides the most straightforward approach to a series of 3-(imino) isoindolinones (3). Ts=4-toluenesulfonyl.

KW - CiH activation

KW - annulations

KW - heterocycles

KW - isocyanide

KW - rhodium

UR - http://www.scopus.com/inward/record.url?scp=80054952941&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80054952941&partnerID=8YFLogxK

U2 - 10.1002/chem.201102475

DO - 10.1002/chem.201102475

M3 - Article

C2 - 21972033

AN - SCOPUS:80054952941

SN - 0947-6539

VL - 17

SP - 12591

EP - 12595

JO - Chemistry - A European Journal

JF - Chemistry - A European Journal

IS - 45

ER -

Rhodium-catalyzed annulation of N-benzoylsulfonamide with isocyanide through C-H activation

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this