Right ventricular outflow tract obstruction: a quest for ideal management

John S.K. Murala, Ryan J. Vela, Tracy Geoffrion, Surpreet Chopra, Soma Guhathakurtha, Thomas Pezzella, Kotturathu Mammen Cherian

Research output: Contribution to journalArticle

1 Scopus citations


Management of right ventricular outflow tract obstruction has undergone much change over the last century. Techniques described in the literature include anatomical repairs and the use of various patches, conduits, and innovative grafts. However, many of these approaches require reoperations or catheter-based interventions, leading to increased morbidity, mortality, and cost. The search for the ideal long-lasting conduit continues and there are new techniques on the horizon, using genetic engineering and nanotechnology. This review discusses the evolution of various techniques for repair of right ventricular outflow tract obstruction, past and current conduits, as well as ongoing research.

Original languageEnglish (US)
JournalAsian Cardiovascular and Thoracic Annals
StateAccepted/In press - Jan 1 2018


  • autologous Transplantation
  • congenital
  • Heart defects
  • homologous
  • Prosthesis design
  • Pulmonary valve
  • Transplantation
  • Ventricular outflow obstruction

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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  • Cite this

    Murala, J. S. K., Vela, R. J., Geoffrion, T., Chopra, S., Guhathakurtha, S., Pezzella, T., & Cherian, K. M. (Accepted/In press). Right ventricular outflow tract obstruction: a quest for ideal management. Asian Cardiovascular and Thoracic Annals. https://doi.org/10.1177/0218492318779963