Rising incidence and aggressive nature of cutaneous malignancies after transplantation: An update on epidemiology, risk factors, management and surveillance

Anthony P. Tufaro, Saïd C. Azoury, Joseph G. Crompton, David M. Straughan, Sashank Reddy, Nijaguna B. Prasad, Gang Shi, Anne C. Fischer

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Although immunosuppression has been a key component to the success of solid-organ transplantation, the morbidity associated with long-term immunosuppression remains a substantial burden, particularly as recipients of transplants live longer. Indeed, malignancy is one of the most common reasons for mortality following transplantation and the most common of these cancers are cutaneous in origin. Recently, the incidence of these malignancies has been on the rise, partly due to the fact that recipients of these transplants are living longer as a result of improvements in surgical technique, immunosuppression and perioperative management. Although there have been initiatives to increase awareness of cutaneous malignancies following transplantation, such programs are not standardized and there continues to be gaps in skin cancer education and post-operative surveillance. This review provides an update on the epidemiology, risk factors, clinical management, prevention and surveillance of cutaneous malignancies.

Original languageEnglish (US)
Pages (from-to)345-352
Number of pages8
JournalSurgical Oncology
Volume24
Issue number4
DOIs
StatePublished - Dec 1 2015

Fingerprint

Risk Management
Epidemiology
Transplantation
Immunosuppression
Skin
Incidence
Skin Neoplasms
Neoplasms
Organ Transplantation
Morbidity
Education
Mortality
Transplant Recipients

Keywords

  • Cutaneous malignancy
  • Immunosuppression
  • Risk factors
  • Surveillance
  • Transplant

ASJC Scopus subject areas

  • Oncology
  • Surgery

Cite this

Rising incidence and aggressive nature of cutaneous malignancies after transplantation : An update on epidemiology, risk factors, management and surveillance. / Tufaro, Anthony P.; Azoury, Saïd C.; Crompton, Joseph G.; Straughan, David M.; Reddy, Sashank; Prasad, Nijaguna B.; Shi, Gang; Fischer, Anne C.

In: Surgical Oncology, Vol. 24, No. 4, 01.12.2015, p. 345-352.

Research output: Contribution to journalArticle

Tufaro, Anthony P. ; Azoury, Saïd C. ; Crompton, Joseph G. ; Straughan, David M. ; Reddy, Sashank ; Prasad, Nijaguna B. ; Shi, Gang ; Fischer, Anne C. / Rising incidence and aggressive nature of cutaneous malignancies after transplantation : An update on epidemiology, risk factors, management and surveillance. In: Surgical Oncology. 2015 ; Vol. 24, No. 4. pp. 345-352.
@article{164e614a02644c57af9cf9f6ef81ebbf,
title = "Rising incidence and aggressive nature of cutaneous malignancies after transplantation: An update on epidemiology, risk factors, management and surveillance",
abstract = "Although immunosuppression has been a key component to the success of solid-organ transplantation, the morbidity associated with long-term immunosuppression remains a substantial burden, particularly as recipients of transplants live longer. Indeed, malignancy is one of the most common reasons for mortality following transplantation and the most common of these cancers are cutaneous in origin. Recently, the incidence of these malignancies has been on the rise, partly due to the fact that recipients of these transplants are living longer as a result of improvements in surgical technique, immunosuppression and perioperative management. Although there have been initiatives to increase awareness of cutaneous malignancies following transplantation, such programs are not standardized and there continues to be gaps in skin cancer education and post-operative surveillance. This review provides an update on the epidemiology, risk factors, clinical management, prevention and surveillance of cutaneous malignancies.",
keywords = "Cutaneous malignancy, Immunosuppression, Risk factors, Surveillance, Transplant",
author = "Tufaro, {Anthony P.} and Azoury, {Sa{\"i}d C.} and Crompton, {Joseph G.} and Straughan, {David M.} and Sashank Reddy and Prasad, {Nijaguna B.} and Gang Shi and Fischer, {Anne C.}",
year = "2015",
month = "12",
day = "1",
doi = "10.1016/j.suronc.2015.09.007",
language = "English (US)",
volume = "24",
pages = "345--352",
journal = "Surgical Oncology",
issn = "0960-7404",
publisher = "Elsevier BV",
number = "4",

}

TY - JOUR

T1 - Rising incidence and aggressive nature of cutaneous malignancies after transplantation

T2 - An update on epidemiology, risk factors, management and surveillance

AU - Tufaro, Anthony P.

AU - Azoury, Saïd C.

AU - Crompton, Joseph G.

AU - Straughan, David M.

AU - Reddy, Sashank

AU - Prasad, Nijaguna B.

AU - Shi, Gang

AU - Fischer, Anne C.

PY - 2015/12/1

Y1 - 2015/12/1

N2 - Although immunosuppression has been a key component to the success of solid-organ transplantation, the morbidity associated with long-term immunosuppression remains a substantial burden, particularly as recipients of transplants live longer. Indeed, malignancy is one of the most common reasons for mortality following transplantation and the most common of these cancers are cutaneous in origin. Recently, the incidence of these malignancies has been on the rise, partly due to the fact that recipients of these transplants are living longer as a result of improvements in surgical technique, immunosuppression and perioperative management. Although there have been initiatives to increase awareness of cutaneous malignancies following transplantation, such programs are not standardized and there continues to be gaps in skin cancer education and post-operative surveillance. This review provides an update on the epidemiology, risk factors, clinical management, prevention and surveillance of cutaneous malignancies.

AB - Although immunosuppression has been a key component to the success of solid-organ transplantation, the morbidity associated with long-term immunosuppression remains a substantial burden, particularly as recipients of transplants live longer. Indeed, malignancy is one of the most common reasons for mortality following transplantation and the most common of these cancers are cutaneous in origin. Recently, the incidence of these malignancies has been on the rise, partly due to the fact that recipients of these transplants are living longer as a result of improvements in surgical technique, immunosuppression and perioperative management. Although there have been initiatives to increase awareness of cutaneous malignancies following transplantation, such programs are not standardized and there continues to be gaps in skin cancer education and post-operative surveillance. This review provides an update on the epidemiology, risk factors, clinical management, prevention and surveillance of cutaneous malignancies.

KW - Cutaneous malignancy

KW - Immunosuppression

KW - Risk factors

KW - Surveillance

KW - Transplant

UR - http://www.scopus.com/inward/record.url?scp=84956785821&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84956785821&partnerID=8YFLogxK

U2 - 10.1016/j.suronc.2015.09.007

DO - 10.1016/j.suronc.2015.09.007

M3 - Article

C2 - 26690824

AN - SCOPUS:84956785821

VL - 24

SP - 345

EP - 352

JO - Surgical Oncology

JF - Surgical Oncology

SN - 0960-7404

IS - 4

ER -