Risk factors for urgency incontinence in women undergoing stress urinary incontinence surgery

Leslie M. Rickey, Liyuan Huang, David D. Rahn, Yvonne Hsu, Heather J. Litman, Elizabeth R. Mueller

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Objective. To determine baseline variables associated with urgency urinary incontinence (UUI) in women presenting for stress urinary incontinence (SUI) surgery. Methods. Baseline data from two randomized trials enrolling 1,252 women were analyzed: SISTEr (fascial sling versus Burch colposuspension) and TOMUS (retropubic versus transobturator midurethral sling). Demographic data, POP-Q measures, and validated measures of symptom severity and quality of life were collected. Charlson Comorbidity Index (CCI) and Patient Health Questionnaire-9 were measured in TOMUS. Multivariate models were constructed with UUI and symptom severity as outcomes. Results. Over two-thirds of subjects reported bothersome UUI at baseline. TOMUS patients with more comorbidities had higher UDI irritative scores (CCI score 0 = 39.4, CCI score 1 = 42.1, and CCI score 2+ = 51.0, P = 0.0003), and higher depression scores were associated with more severe UUI. Smoking, parity, prior incontinence surgery/treatment, prolapse stage, and incontinence episode frequency were not independently associated with UUI. Conclusions. There were no modifiable risk factors identified for patient-reported UUI in women presenting for SUI surgery. However, the direct relationships between comorbidity level, depression, and worsening of UUI/urgency symptoms may represent targets for preoperative intervention. Further research is necessary to elucidate the pathophysiologic mechanisms that explain the associations between these medical conditions and bladder function.

Original languageEnglish (US)
Article number567375
JournalAdvances in Urology
DOIs
StatePublished - 2013

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Stress Urinary Incontinence
Urinary Incontinence
Comorbidity
Suburethral Slings
Depression
Prolapse
Parity
Urinary Bladder
Smoking
Quality of Life
Demography
Health
Research

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Urology

Cite this

Risk factors for urgency incontinence in women undergoing stress urinary incontinence surgery. / Rickey, Leslie M.; Huang, Liyuan; Rahn, David D.; Hsu, Yvonne; Litman, Heather J.; Mueller, Elizabeth R.

In: Advances in Urology, 2013.

Research output: Contribution to journalArticle

Rickey, Leslie M. ; Huang, Liyuan ; Rahn, David D. ; Hsu, Yvonne ; Litman, Heather J. ; Mueller, Elizabeth R. / Risk factors for urgency incontinence in women undergoing stress urinary incontinence surgery. In: Advances in Urology. 2013.
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