Risk of incontinence with transurethral resection of the prostate after radiation therapy for prostate cancer

Hetal Patel, Anuj V. Peddada, Philippe E. Zimmern, Reynaldo Hernandez, Robert Kagan

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Background: It has been reported that transurethral resection of the prostate (TURP) after definitive radiation therapy for prostate cancer is associated with a significant risk of incontinence. The presumed reason for incontinence is external sphincter damage from TURP or pre-existing damage from either extension of prostate cancer or radiation therapy. Methods: We reviewed seven recent cases of TURP for bladder outlet obstruction in patients who had undergone radiation therapy for clinical stage T3-4M0N0 adenocarcinoma of the prostate. All seven men progressed to either chronic retention or debilitating obstructive symptoms with weak peak flows from 3.4 to 5.1 cc/s (mean 4 cc/s). Each of them subsequently underwent a limited TURP. Results: Voiding symptoms were reduced in all patients and peak flows were improved to 6.3 to 20 cc/s (mean 14.8 cc/s) with mean follow-up 35 m. No patient developed stress urinary incontinence postoperatively. Conclusion: These results suggest that TURP can be performed successfully after radiation therapy with minimal risk of stress incontinence.

Original languageEnglish (US)
Pages (from-to)127-129
Number of pages3
JournalJournal of Surgical Oncology
Volume64
Issue number2
DOIs
StatePublished - Feb 1 1997

Keywords

  • adenocarcinoma of prostate
  • radiotherapy
  • stress incontinence

ASJC Scopus subject areas

  • Surgery
  • Oncology

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