Risk of Unplanned Hospital Encounters in Patients Treated With Radiotherapy for Head and Neck Squamous Cell Carcinoma

Zachary R. Moore, Nhat-Long Lam Pham, Jennifer L Shah, Lucien A Nedzi, Baran D Sumer, Andrew Day, Saad Khan, David J Sher

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Context: Radiotherapy is highly effective for treating squamous cell carcinoma of the head and neck but is often associated with significant toxicities and severe morbidity. Unplanned emergency department (ED) visits and hospitalizations are common during treatment and come with a substantial financial and health burden as well as the potential for impaired long-term outcomes due to treatment disruption. Objectives: The objective of this study was to identify patient, disease, and treatment characteristics that were associated with ED encounters and admissions. Methods: A cohort of 462 patients with cancer of the head and neck treated with radiotherapy at UT Southwestern between 2010 and 2015 was retrospectively analyzed. The risks of ED visits, admissions, multiple admissions, and extended admissions were determined. Risk factors for an unplanned hospital encounter were analyzed using univariate and multivariate logistic regression. Results: Overall, 36% of patients had an unplanned hospital encounter during the treatment window. Patients with advanced disease, those with high comorbidity score, and those treated with concurrent chemotherapy were more likely to have unplanned admissions/ED visits. Social factors such as marital status, smoking status, and registration in the public hospital system were also strongly associated with admissions and multiple encounters. Conclusion: The high rate of admissions and ED visits emphasizes the importance of anticipating and managing toxicities during treatment. Social factors have a strong association with unplanned encounters and may present opportunities for targeted interventions to reduce admissions for patients at highest risk.

Original languageEnglish (US)
Pages (from-to)738-745.e3
JournalJournal of Pain and Symptom Management
Volume57
Issue number4
DOIs
StatePublished - Apr 1 2019

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Hospital Emergency Service
Radiotherapy
Therapeutics
Patient Admission
Public Hospitals
Marital Status
Head and Neck Neoplasms
Comorbidity
Hospitalization
Logistic Models
Smoking
Carcinoma, squamous cell of head and neck
Morbidity
Drug Therapy
Health

Keywords

  • chemoradiation
  • complications
  • head and neck cancer
  • Hospitalizations
  • radiation therapy

ASJC Scopus subject areas

  • Nursing(all)
  • Clinical Neurology
  • Anesthesiology and Pain Medicine

Cite this

Risk of Unplanned Hospital Encounters in Patients Treated With Radiotherapy for Head and Neck Squamous Cell Carcinoma. / Moore, Zachary R.; Pham, Nhat-Long Lam; Shah, Jennifer L; Nedzi, Lucien A; Sumer, Baran D; Day, Andrew; Khan, Saad; Sher, David J.

In: Journal of Pain and Symptom Management, Vol. 57, No. 4, 01.04.2019, p. 738-745.e3.

Research output: Contribution to journalArticle

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