The results of pretreatment with drugs having selective action on brain biogenic amine levels on the subsequent effects of acute marijuana treatment were assessed for behavior and EEG measures. Behavioral changes and alterations in the spontaneous EEG indicated that pretreatment with drugs affecting brain levels of 5-HT was most effective in altering the dual properties of acute marijuana treatment. The present findings support the interpretation that the availability of serotonin interacts with the effects of acute marijuana treatment but do not eliminate the possible involvement of other neurotransmitters in the action of marijuana.
|Original language||English (US)|
|Number of pages||5|
|Journal||Electroencephalography and Clinical Neurophysiology|
|State||Published - Dec 1975|
ASJC Scopus subject areas
- Clinical Neurology