ROLE OF TECHNETIUM-99m STANNOUS PYROPHOSPHATE IN MYOCARDIAL IMAGING TO RECOGNIZE, LOCALIZE AND IDENTIFY EXTENSION OF ACUTE MYOCARDIAL INFARCTION IN PATIENTS.

James T. Willerson, Robert W. Parkey, Frederick J. Bonte, Ernest M. Stokely, L. Maximilian Buja

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Two hundred sixty six patients admitted to Parkland Memorial Hospital, Dallas, Texas with chest pain of varying etiology were studied. Approximately two-thirds of these patients were imaged at their bedside in the coronary care unit utilizing a portable Nuclear Data scintillation camera; the others were imaged in the Nuclear Medicine Department using a Searle Radiographics Inc. Pho/Gamma HP scintillati camera with a 16,000 hole ″high resolution″ collimator. The scintillation camera is interfaced to a PDP-81 computer with 12 K of core. Images are placed on 7 track magnetic tape for later retrieval. The computer processing utilizes image enhancement to help define the margins of the lesion. Each patient was imaged in the anterior, lateral and one or more left anterior oblique projections one hour after the intravenous injection of 15 MiCi **9**9**mTc tagged to 5 mg of stannous pyrophosphate (PYP) with continuous ECG monitoring. No arrhythmia or obvious side effects were observed from either the injection of the radionuclide or from the imaging process itself. The imaging time for 3-5 views was approximately 15 minutes. The myocardial scintigrams were obtained from 12 hours to 14 days after the onset of symptoms suggestive of possible myocardial infarction. In patients with technically appropriate **9**9**mTc-PYP scintigrams, infarct size was measured by planimetering the area of increased **9**9**mTc-PYP uptake and then expressing infarct size in Cm**2.

Original languageEnglish (US)
Title of host publicationSPIE Semin Proc
Pages285-291
Number of pages7
Volume72
StatePublished - 1975
EventCardiovasc Imaging and Image Process, Theory and Pract $-$ 1975 - Stanford, CA, USA
Duration: Jul 10 1975Jul 12 1975

Other

OtherCardiovasc Imaging and Image Process, Theory and Pract $-$ 1975
CityStanford, CA, USA
Period7/10/757/12/75

ASJC Scopus subject areas

  • Engineering(all)

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    Willerson, J. T., Parkey, R. W., Bonte, F. J., Stokely, E. M., & Buja, L. M. (1975). ROLE OF TECHNETIUM-99m STANNOUS PYROPHOSPHATE IN MYOCARDIAL IMAGING TO RECOGNIZE, LOCALIZE AND IDENTIFY EXTENSION OF ACUTE MYOCARDIAL INFARCTION IN PATIENTS. In SPIE Semin Proc (Vol. 72, pp. 285-291)