Role of the alanine at position 363 of cytochrome P450 2B2 in influencing the NADPH- and hydroperoxide-supported activities

Medicine & Life Sciences

• steroid 16-beta-hydroxylase 100%
• cumene hydroperoxide 90%
• Benzphetamine 76%
• NADP 60%
• Alanine 56%
• Hydrogen Peroxide 56%
• octylamine 41%
• Hydroxylation 38%
• Demethylation 26%
• 2-phenyl-2-propanol 26%
• 7-ethoxy-4-trifluoromethylcoumarin 23%
• Cytochrome P-450 CYP2B1 16%
• Cytochromes b5 16%
• 2-Propanol 15%
• Propylene Glycol 14%
• 9,10-Dimethyl-1,2-benzanthracene 14%
• Proteins 8%
• Ligands 7%
• Escherichia coli 7%
• Mutation 6%
• Enzymes 6%

Chemical Compounds

• Benzphetamine 90%
• Cytochrome P450 59%
• Alanine 53%
• Cumene 52%
• Cumene Hydroperoxide 38%
• 2-phenyl-1,2-propanediol 31%
• Cytochrome B5 19%
• Anthracene 13%
• Mutation 11%
• Protein 11%
• Pharmacological Metabolism 10%
• Cleavage 9%
• Substitution Reaction 8%
• Ligand 6%
• Mixture 6%