Role of the hMLH1 DNA mismatch repair protein in fluoropyrimidine-mediated cell death and cell cycle responses

Medicine & Life Sciences

• DNA Mismatch Repair 100%
• 5-fluoro-2'-deoxyuridine 91%
• Cell Cycle 66%
• Cell Death 63%
• Proteins 30%
• Turcot syndrome 20%
• 1,2-di-(4-sulfamidophenyl)-4-butylpyrazolidine-3,5-dione 20%
• G2 Phase Cell Cycle Checkpoints 19%
• Thymidine 13%
• Fluorouracil 13%
• Colorectal Neoplasms 11%
• Cyclin B1 9%
• Staining and Labeling 9%
• HCT116 Cells 9%
• Uridine 8%
• Pulsed Field Gel Electrophoresis 8%
• Propidium 8%
• Double-Stranded DNA Breaks 8%
• DNA 7%
• Cell Cycle Checkpoints 6%
• DNA Repair 6%
• Colonic Neoplasms 6%
• DNA Damage 6%
• Monoclonal Antibodies 5%
• RNA 4%
• Neoplasms 4%
• Apoptosis 4%
• Survival 3%
• Pharmaceutical Preparations 2%