Rosai-Dorfman disease of the gastrointestinal tract: Report of a case and review of the literature

Houda Alatassi, Mukunda B. Ray, Susan Galandiuk, Sunati Sahoo

Research output: Contribution to journalReview articlepeer-review

18 Scopus citations

Abstract

Rosai-Dorfman disease (RDD) is a rare, acquired disease of unknown etiology that affects primarily chifdren and young adults. It is characterized by a proliferation of distinctive histiocytes in the lymph nodes and/or extranodal sites, involvement of the gastrointestinal tract is rare. We report a case of RDD in a 60-year-old woman who presented with hematochezia and was found to have RDD of the rectum presenting as a rectal mass. This report highlights the current pathogenetic mechanisms, immunohistochemical markers, and the gastrointestinal manifestations of RDD.

Original languageEnglish (US)
Pages (from-to)95-99
Number of pages5
JournalInternational Journal of Surgical Pathology
Volume14
Issue number1
DOIs
StatePublished - Jan 1 2006

Keywords

  • Gastrointestinal tract
  • Rosai-Dorfman disease
  • Sinus histiocytosis with massive lymphadenopathy

ASJC Scopus subject areas

  • Anatomy
  • Surgery
  • Pathology and Forensic Medicine

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